SCHEMBL2638014

SCHEMBL2638014

CCCCCCCCCCCCCC(=O)OP(=O)(OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCC

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ FABP3 P05413 1/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.53
▸ NR5A2 O00482 1/20 0.53
▸ NR5A1 Q13285 1/20 0.53
▸ LMNA P02545 1/20 0.53
▸ ESR1 P03372 1/20 0.53
▸ ADORA3 P0DMS8 1/20 0.53
▸ CDC25A P30304 1/20 0.53
▸ AGTR1 P30556 1/20 0.53
▸ AKT1 P31749 1/20 0.53
▸ ADRA1A P35348 1/20 0.53
▸ KCNH2 Q12809 1/20 0.53
▸ MAPT P10636 1/20 0.51
▸ DGKA P23743 1/20 0.50
▸ RECQL P46063 1/20 0.49
▸ PLA2G1B P04054 1/20 0.47
▸ PLA2G2A P14555 1/20 0.47
▸ PLA2G10 O15496 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3983857 1.00 FABP3 (0.54) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL31432721 1.00 FABP3 (0.54) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL1768918 1.00 FABP3 (0.54) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL3182833 1.00 FABP3 (0.54) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL22721397 1.00 FABP3 (0.54) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL1341976 1.00 FABP3 (0.54) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL6666152 0.98 FABP3 (0.52) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL617162 0.92 ALDH1A1 (0.53) FABP3SMN1; SMN2NR5A2NR5A1
SCHEMBL1643923 0.87 FABP3 (0.62) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL5475892 0.87 FABP3 (0.62) FABP3SMN1; SMN2NR5A2NR5A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10844109-B2 Method for producing erythrocyte proteins INSTITUT NATIONAL TRANSFUSION SANGUINE (FR) 2020-11-24 — — US claimed
US-20190105287-A1 Liposomal Curcumin for Treatment of Cancer BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2019-04-11 — — US claimed
EP-4642434-A2 LIPID COMPOSITIONS ON THE BASIS OF IONIZABLE LIPIDS, USE FOR DELIVERY TO IMMUNE CELLS Life Technologies Corporation (US) 2025-11-05 — — EP disclosed
EP-4565572-A1 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2025-06-11 — — EP disclosed
EP-4547282-A1 LIPID COMPOSITIONS FOR IN VIVO DELIVERY Life Technologies Corporation (US) 2025-05-07 — — EP disclosed
US-20250092143-A1 GENETICALLY ENGINEERED MULTIFUNCTIONAL EXOSOMES FOR IMMUNOTHERAPY UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2025-03-20 — — US disclosed
WO-2025047645-A1 METHOD FOR SIMULTANEOUS DETECTION OF BIOMOLECULES USING TEMPERATURE-RESPONSIVE FLUORESCENT PARTICLES 学校法人早稲田大学 2025-03-06 — — WO disclosed
WO-2024182731-A1 INJECTABLE COMPOSITIONS OF VITAMERS OF VITAMIN B12 AND USES THEREOF NEVAKAR INJECTABLES INC. (US) 2024-09-06 — — WO disclosed
US-20240263196-A1 Lipid Compositions and Methods for Delivery to Immune Cells Life Technologies Corporation 2024-08-08 — — US disclosed
US-12040170-B2 Methods and apparatuses for deconvolution of mass spectrometry data PROTEIN METRICS, LLC (US) 2024-07-16 — — US disclosed
WO-2024145435-A2 LIPID COMPOSITIONS AND METHODS FOR DELIVERY TO IMMUNE CELLS Life Technologies Corporation (US) 2024-07-04 — — WO disclosed
EP-1994147-A1 USE OF A THERMOSTABLE PHOSPHOLIPASE IN THE DEGUMMING OF AN OIL OR FAT, AND A METHOD FOR OBTAINING A THERMOSTABLE PHOSPHOLIPASE Sued-Chemie AG (DE) 2008-11-26 — — EP disclosed
US-20080138400-A1 Curcumin analog or metabolite microencapsulated by a polyethylene glycolated liposome of dimyristoyl phosphatidylcholine, cholesterol, and dimyristoyl phsphatidylethanolamine; anticarcinogenic and antiproliferative agents; parenteral colloidal drug delivery system providing improved bioavailability BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2008-06-12 — — US disclosed
US-20080103213-A1 LIPOSOMAL CURCUMIN FOR TREATMENT OF NEUROFIBROMATOSIS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2008-05-01 — — US disclosed
WO-2007059927-A1 USE OF A THERMOSTABLE PHOSPHOLIPASE IN THE DEGUMMING OF AN OIL OR FAT, AND A METHOD FOR OBTAINING A THERMOSTABLE PHOSPHOLIPASE Süd-Chemie AG (DE) 2007-05-31 — — WO disclosed
EP-1161688-B1 COLORIMETRIC DETECTION METHOD UNIV BEN GURION (IL) 2007-02-28 — — EP disclosed
US-20060067998-A1 Curcumin analog or metabolite microencapsulated by a polyethylene glycolated liposome of dimyristoyl phosphatidylcholine, cholesterol, and dimyristoyl phsphatidylethanolamine; parenteral colloidal drug delivery system providing improved bioavailability BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2006-03-30 — — US disclosed
WO-2004080396-A2 LIPOSOMAL CURCUMIN FOR TREATMENT OF CANCER THE UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER (US) 2004-09-23 — — WO disclosed
EP-1161688-A2 COLORIMETRIC DETECTION METHOD BEN-GURION UNIVERSITY OF THE NEGEV (IL) 2001-12-12 — — EP disclosed
WO-2000055623-A2 COLORIMETRIC DETECTION METHOD BEN-GURION UNIVERSITY OF THE NEGEV (IL) 2000-09-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060067998-A1 Curcumin analog or metabolite microencapsulated by a polyethylene glycolated liposome of dimyristoyl phosphatidylcholine, cholesterol, and dimyristoyl phsphatidylethanolamine; parenteral colloidal drug delivery system providing improved bioavailability PNLIP, SGMS2, SGMS1 FABP3 430/4885SMN1; SMN2 1122/4885NR5A2 3636/4885
US-20190105287-A1 Liposomal Curcumin for Treatment of Cancer PNLIP, BRCA1, IAPP FABP3 320/4885SMN1; SMN2 571/4885NR5A2 2329/4885
US-20080138400-A1 Curcumin analog or metabolite microencapsulated by a polyethylene glycolated liposome of dimyristoyl phosphatidylcholine, cholesterol, and dimyristoyl phsphatidylethanolamine; anticarcinogenic and antiproliferative agents; parenteral colloidal drug delivery system providing improved bioavailability LCAT, SGMS2, SGMS1 FABP3 572/4885SMN1; SMN2 2690/4885NR5A2 3393/4885
US-20080103213-A1 LIPOSOMAL CURCUMIN FOR TREATMENT OF NEUROFIBROMATOSIS MEN1, VHL, CALM1 FABP3 845/4885SMN1; SMN2 354/4885NR5A2 2544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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