SCHEMBL1768918

SCHEMBL1768918

CCCCCCCCCCCCCCCCCC(=O)OP(=O)(OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ FABP3 P05413 1/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.53
▸ NR5A2 O00482 1/20 0.53
▸ NR5A1 Q13285 1/20 0.53
▸ LMNA P02545 1/20 0.53
▸ ESR1 P03372 1/20 0.53
▸ ADORA3 P0DMS8 1/20 0.53
▸ CDC25A P30304 1/20 0.53
▸ AGTR1 P30556 1/20 0.53
▸ AKT1 P31749 1/20 0.53
▸ ADRA1A P35348 1/20 0.53
▸ KCNH2 Q12809 1/20 0.53
▸ MAPT P10636 1/20 0.51
▸ DGKA P23743 1/20 0.50
▸ RECQL P46063 1/20 0.49
▸ PLA2G1B P04054 1/20 0.47
▸ PLA2G2A P14555 1/20 0.47
▸ PLA2G10 O15496 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2638014 1.00 FABP3 (0.54) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL3983857 1.00 FABP3 (0.54) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL31432721 1.00 FABP3 (0.54) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL3182833 1.00 FABP3 (0.54) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL22721397 1.00 FABP3 (0.54) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL1341976 1.00 FABP3 (0.54) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL6666152 0.98 FABP3 (0.52) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL617162 0.92 ALDH1A1 (0.53) FABP3SMN1; SMN2NR5A2NR5A1
SCHEMBL1643923 0.87 FABP3 (0.62) FABP3SMN1; SMN2NR5A2NR5A1LMNA
SCHEMBL5475892 0.87 FABP3 (0.62) FABP3SMN1; SMN2NR5A2NR5A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3893909-A2 KRAS VARIANT MRNA MOLECULES CureVac AG (DE) 2021-10-20 — — EP claimed
WO-2020123300-A2 KRAS VARIANT MRNA MOLECULES ELI LILLY AND COMPANY (US) 2020-06-18 — — WO claimed
US-5626867-A LIPOSOME FOR CYTOTOXIC AGENTS MAX-PLANCK GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 1997-05-06 — — US claimed
US-12528855-B2 KRAS variant mRNA molecules CureVac SE (DE) 2026-01-20 — — US disclosed
EP-4636090-A1 UTR FOR IMPROVING TRANSLATION EFFICIENCY AND/OR STABILITY OF RNA MOLECULE AND USE THEREOF Shenzhen Shenxin Biotechnology Co., Ltd. (CN) 2025-10-22 — — EP disclosed
WO-2025047645-A1 METHOD FOR SIMULTANEOUS DETECTION OF BIOMOLECULES USING TEMPERATURE-RESPONSIVE FLUORESCENT PARTICLES 学校法人早稲田大学 2025-03-06 — — WO disclosed
US-20220340641-A1 KRAS VARIANT MRNA MOLECULES CUREVAC AG (DE) 2022-10-27 — — US disclosed
US-11369697-B2 Liposome nanoparticles for tumor magnetic resonance imaging UNITED KINGDOM RESEARCH AND INNOVATION (GB) 2022-06-28 — — US disclosed
EP-3893909-A2 KRAS VARIANT MRNA MOLECULES CureVac AG (DE) 2021-10-20 — — EP disclosed
US-10918599-B2 Serum-stable compositions and methods for light-triggered release of materials THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2021-02-16 — — US disclosed
EP-3283056-B1 NANOSTRUCTURES COMPRISING COBALT PORPHYRIN-PHOSPHOLIPID CONJUGATES AND POLYHISTIDINE-TAGS THE RESEARCH FOUNDATION FOR THE STATE UNIV OF NEW YORK UNIV AT BUFFALO (US) 2020-12-23 — — EP disclosed
US-20130129636-A1 Novel Liposome Nanoparticles for Tumor Magnetic Resonance Imaging IMPERIAL INNOVATIONS LIMITED (GB) 2013-05-23 — — US disclosed
EP-2501415-A1 LIPOSOME NANOPARTICLES FOR TUMOR MAGNETIC RESONANCE IMAGING Medical Research Council (GB) 2012-09-26 — — EP disclosed
EP-2338525-A2 Remote detection of substance delivery to cells California Pacific Medical Center (US) 2011-06-29 — — EP disclosed
WO-2011061541-A1 LIPOSOME NANOPARTICLES FOR TUMOR MAGNETIC RESONANCE IMAGING MEDICAL RESEARCH COUNCIL (GB) 2011-05-26 — — WO disclosed
US-20110104261-A1 REMOTE DETECTION OF SUBSTANCE DELIVERY TO CELLS SUTTER WEST BAY HOSPITALS, DBA 2011-05-05 — — US disclosed
EP-1648299-A4 REMOTE DETECTION OF SUBSTANCE DELIVERY TO CELLS CALIFORNIA PACIFIC MED CENTER (US) 2008-10-22 — — EP disclosed
EP-1648299-A1 REMOTE DETECTION OF SUBSTANCE DELIVERY TO CELLS California Pacific Medical Center (US) 2006-04-26 — — EP disclosed
US-20050112065-A1 Remote detection of substance delivery to cells SUTTER WEST BAY HOSPITALS, DBA CALIFORNIA PACIFIC MEDICAL CENTER 2005-05-26 — — US disclosed
WO-2005016141-A1 REMOTE DETECTION OF SUBSTANCE DELIVERY TO CELLS CALIFORNIA PACIFIC MEDICAL CENTER (US) 2005-02-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528855-B2 KRAS variant mRNA molecules KRAS, NRAS, TP53 FABP3 1397/4885SMN1; SMN2 1483/4885NR5A2 3974/4885
US-11369697-B2 Liposome nanoparticles for tumor magnetic resonance imaging PHOSPHO1, SGMS1, SGMS2 FABP3 2257/4885SMN1; SMN2 1993/4885NR5A2 3233/4885
US-20220340641-A1 KRAS VARIANT MRNA MOLECULES KRAS, NRAS, APC FABP3 4547/4885SMN1; SMN2 2467/4885NR5A2 2920/4885
US-10918599-B2 Serum-stable compositions and methods for light-triggered release of materials PLTP, PHOSPHO1, TTPA FABP3 55/4885SMN1; SMN2 2392/4885NR5A2 4150/4885
US-20130129636-A1 Novel Liposome Nanoparticles for Tumor Magnetic Resonance Imaging PHOSPHO1, SGMS1, SGMS2 FABP3 1328/4885SMN1; SMN2 1418/4885NR5A2 3571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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