Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743252 | 0.81 | ALDH1A1 (0.70) | MEN1KMT2ASMN1; SMN2BDKRB1NPC1 | |
| SCHEMBL7273972 | 0.81 | SRD5A2 (0.52) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL7264522 | 0.79 | HPGD (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL3989124 | 0.76 | HTT (0.47) | MEN1KMT2ASMN1; SMN2RAB9ATDP1 | |
| SCHEMBL9416106 | 0.75 | SRD5A2 (0.50) | KMT2ASMN1; SMN2TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL23926254 | 0.75 | KMT2A (0.55) | MEN1KMT2ASMN1; SMN2BDKRB1NPC1 | |
| SCHEMBL28293837 | 0.75 | NPC1 (0.48) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7910275 | 0.75 | MAPT (0.42) | KMT2ANPC1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL2382559 | 0.75 | LMNA (0.54) | MEN1KMT2ASMN1; SMN2RAB9ATDP1 | |
| SCHEMBL10890401 | 0.75 | LMNA (0.54) | MEN1KMT2ASMN1; SMN2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |