SCHEMBL398402

SCHEMBL398402

CCC(CBr)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL6064355 0.89 CA2 (0.43)
SCHEMBL348796 0.82
SCHEMBL6114 0.82
Ethyl Bromo Acetate SCHEMBL31037865 0.82 ALDH1A1 (0.63)
SCHEMBL11328439 0.80 TSHR (0.40)
SCHEMBL8573707 0.79
SCHEMBL4858248 0.79
SCHEMBL97792 0.79
Hydrochloric Acid SCHEMBL2210811 0.79
SCHEMBL1506860 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114105926-A Synthesis method of deuterium-labeled delta-nonalactone 上海化工研究院有限公司 2022-03-01 CN claimed
US-12486278-B2 MASP-2 inhibitors and methods of use OMEROS CORPORATION (US) 2025-12-02 US disclosed
US-20250333390-A1 BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS ALBIREO AB (SE) 2025-10-30 US disclosed
US-12202809-B2 Benzothia(di)azepine compounds and their use as bile acid modulators ALBIREO AB (SE) 2025-01-21 US disclosed
US-12180318-B2 Imidazolium zwitterion polymerizable compounds and ophthalmic devices incorporating them JOHNSON & JOHNSON VISION CARE, INC. (US) 2024-12-31 US disclosed
EP-4165446-B9 IMIDAZOLIUM ZWITTERION POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES INCORPORATING THEM JOHNSON & JOHNSON VISION CARE (US) 2024-07-10 EP disclosed
US-20240207412-A1 DIELS-ALDER CONJUGATION METHODS REGENERON PHARMACEUTICALS, INC. (US) 2024-06-27 US disclosed
CN-114761079-B Benzothiazepine compounds and their use as bile acid modulators 阿尔比里奥公司 2024-05-28 CN disclosed
US-20240109854-A1 BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS ALBIREO AB (SE) 2024-04-04 US disclosed
EP-4165446-B1 IMIDAZOLIUM ZWITTERION POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES INCORPORATING THEM JOHNSON & JOHNSON VISION CARE (US) 2024-04-03 EP disclosed
US-4460781-A PREPARATION OF PYRAZOLOBENZAZEPINES HOFFMANN-LA ROCHE INC. (US) 1984-07-17 US disclosed
EP-0045521-B1 PYRAZOLOBENZAZEPINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1984-06-27 EP disclosed
US-4440787-A 2',4'-DIFLUORO-4-BIPHENYL/OXYPROPIONIC ACID; NONTOXIC AUSONIA FARMACEUTICI S.R.L. (IT) 1984-04-03 US disclosed
EP-0080889-A1 Herbicidal compositions containing and method using phosphonoalkanoic acids, esters and salts thereof PHILIP A. HUNT CHEMICAL CORPORATION (US) 1983-06-08 EP disclosed
EP-0080010-A1 Novel compounds with antiinflammatory and analgesic activity, process for the preparation thereof and pharmaceutical compositions therefrom AUSONIA FARMACEUTICI S.r.l. (IT) 1983-06-01 EP disclosed
EP-0078704-A1 Intermediates in the synthesis of vitamin D derivatives RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) 1983-05-11 EP disclosed
US-4379765-A SEDATIVES, ANXIETY HOFFMANN-LA ROCHE INC. (US) 1983-04-12 US disclosed
EP-0062018-A1 Novel phenyl-piperidines Aktiebolaget Hässle (SE) 1982-10-06 EP disclosed
US-4213894-A IMMUNOASSAY FOR DIPHENYLHYDANTOIN MILES LABORATORIES, INC. (US) 1980-07-22 US disclosed
US-4139634-A ANTIDEPRESSANTS, ANTIAGGRESSION AGENTS, ANESTHETICS LABAZ (FR) 1979-02-13 US disclosed