Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.75 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP12 | P39900 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7183176 | 0.86 | GPR84 (1.00) | GPR84MMP2MMP1MMP9MMP12 | |
| SCHEMBL11129320 | 0.86 | GPR84 (1.00) | GPR84MMP2MMP1MMP9MMP12 | |
| SCHEMBL10681299 | 0.86 | GPR84 (1.00) | GPR84MMP2MMP1MMP9MMP12 | |
| SCHEMBL2295495 | 0.80 | GPR84 (0.89) | GPR84MMP2MMP1MMP9MMP12 | |
| SCHEMBL28002724 | 0.72 | MMP2 (0.65) | GPR84MMP2MMP1MMP9MMP12 | |
| SCHEMBL5935742 | 0.71 | GPR84 (0.58) | GPR84MMP2MMP1MMP9MMP12 | |
| SCHEMBL23250535 | 0.70 | ESR1 (0.77) | TSHRALDH1A1LMNAMAPK1ESR1 | |
| SCHEMBL20695635 | 0.70 | TSHR (0.73) | TSHRALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL20695622 | 0.70 | TSHR (0.73) | TSHRALDH1A1LMNAMAPK1KDM4E | |
| SCHEMBL20695609 | 0.70 | TSHR (0.73) | TSHRALDH1A1LMNAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609677-B2 | Molecules for the photodynamic treatment of tumors and hyperplasias | Yagna Limited (GB) | 2013-12-17 | — | — | US | disclosed |
| US-20130226136-A1 | Molecules for the Photodynamic Treatment of Tumors and Hyperplasias | HUMANITARIAN SCIENTIFIC LLC | 2013-08-29 | — | — | US | disclosed |
| US-8410125-B2 | Sulfonated precursors of thymidine for the treatment of epithelial hyperplasias | Yagna Limited (GB) | 2013-04-02 | — | — | US | disclosed |
| US-20110053965-A1 | SULFONATED PRECURSORS OF THYMIDINE FOR THE TREATMENT OF EPITHELIAL HYPERPLASIAS | ASKLEPIUS LIMITED (GB) | 2011-03-03 | — | — | US | disclosed |
| WO-2009060186-A1 | SULFONATED PRECURSORS OF THYMIDINE FOR THE TREATMENT OF EPITHELIAL HYPERPLASIAS | ASKLEPUIS LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |