Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 6/20 | 1.00 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP12 | P39900 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11129320 | 1.00 | GPR84 (1.00) | GPR84MMP1MMP9MMP12ALDH1A1 | |
| SCHEMBL10681299 | 1.00 | GPR84 (1.00) | GPR84MMP1MMP9MMP12ALDH1A1 | |
| SCHEMBL2295495 | 0.94 | GPR84 (0.89) | GPR84MMP1MMP9MMP12ALDH1A1 | |
| SCHEMBL3984385 | 0.86 | GPR84 (0.75) | GPR84MMP1MMP9MMP12ALDH1A1 | |
| SCHEMBL1461344 | 0.78 | GPR84 (0.63) | GPR84ALDH1A1TSHRLMNACYP1A2 | |
| SCHEMBL11129245 | 0.74 | CYP1A2 (0.60) | GPR84ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL5935742 | 0.73 | GPR84 (0.58) | GPR84MMP1MMP9MMP12ALDH1A1 | |
| SCHEMBL4283121 | 0.73 | CYP1A2 (0.64) | GPR84ALDH1A1TSHRKDM4ELMNA | |
| SCHEMBL23250535 | 0.72 | ESR1 (0.77) | ALDH1A1TSHRLMNAMAPK1ESR1 | |
| SCHEMBL22289827 | 0.72 | ESR1 (0.77) | ALDH1A1TSHRLMNAMAPK1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1288238-A1 | Compositions of matter having bioactive properties | Schmitz, Robert A. (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6299892-B1 | INCORPORATING INTO DELIVERY VEHICLES SUITABLE FOR EFFECTING DESIRED ANTIMICROBIAL USE, SOAPS AND DETERGENTS | SCHMITZ ROBERT A (US) | 2001-10-09 | — | — | US | disclosed |