Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.32 |
| ▸ | INMT | O95050 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654257 | 0.81 | LMNA (0.40) | LMNATSHRCYP1A2PRKCAINMT | |
| SCHEMBL4931493 | 0.68 | TSHR (0.32) | TSHR | |
| Maleic Acid SCHEMBL9767753 | 0.65 | TSHR (0.46) | TSHRCYP1A2INMT | |
| Fumaric Acid SCHEMBL9767759 | 0.65 | TSHR (0.46) | TSHRCYP1A2INMT | |
| SCHEMBL3258347 | 0.64 | TSHR (0.40) | TSHR | |
| Maleic Acid SCHEMBL5166062 | 0.63 | CA1 (0.64) | LMNATSHRCYP1A2INMT | |
| Fumaric Acid SCHEMBL30153854 | 0.63 | CA1 (0.64) | LMNATSHRCYP1A2INMT | |
| Fumaric Acid SCHEMBL301635 | 0.63 | CA1 (0.64) | LMNATSHRCYP1A2INMT | |
| SCHEMBL4912011 | 0.62 | — | — | |
| SCHEMBL6209797 | 0.61 | LMNA (0.38) | LMNATSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032621-B1 | CROSS-LINKABLE THERMOPLASTIC POLYURETHANES | HUNTSMAN INT LLC (US) | 2019-08-14 | — | — | EP | claimed |
| US-20090197000-A1 | CROSS-LINKABLE THERMOPLASTIC POLYURETHANES | HUNTSMAN INTERNATIONAL LLC (US) | 2009-08-06 | — | — | US | claimed |
| EP-2032621-A1 | CROSS-LINKABLE THERMOPLASTIC POLYURETHANES | Huntsman International LLC (US) | 2009-03-11 | — | — | EP | claimed |
| WO-2007144292-A1 | CROSS-LINKABLE THERMOPLASTIC POLYURETHANES | HUNTSMAN INTERNATIONAL LLC (US) | 2007-12-21 | — | — | WO | claimed |