Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573528 | 0.75 | — | — | |
| SCHEMBL4931493 | 0.75 | TSHR (0.32) | TSHRTP53EGLN1EGLN3 | |
| SCHEMBL3260748 | 0.67 | TSHR (0.44) | TSHRTP53EGLN1EGLN3THRB | |
| Fumaric Acid SCHEMBL2046433 | 0.61 | TSHR (1.00) | TSHRTP53EGLN1EGLN3THRB | |
| Maleic Acid SCHEMBL2046430 | 0.61 | TSHR (1.00) | TSHRTP53EGLN1EGLN3THRB | |
| Maleic Acid SCHEMBL2046432 | 0.61 | TSHR (1.00) | TSHRTP53EGLN1EGLN3THRB | |
| Fumaric Acid SCHEMBL615 | 0.61 | — | — | |
| Maleic Acid SCHEMBL613 | 0.61 | — | — | |
| Fumaric Acid SCHEMBL6875 | 0.61 | TSHR (1.00) | TSHRTP53EGLN1EGLN3THRB | |
| Maleic Acid SCHEMBL20487516 | 0.61 | TSHR (1.00) | TSHRTP53EGLN1EGLN3THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130116405-A1 | COMPOSITIONS COMPRISING MODIFIED COLLAGEN AND USES THEREFOR | THE JOHNS HOPKINS UNIVERSITY (US) | 2013-05-09 | — | — | US | claimed |
| US-20080038306-A1 | Fluidic Tissue Augmentation Compositions and Methods | JOHN HOPKINS UNIVERSITY | 2008-02-14 | — | — | US | claimed |
| EP-3638705-B1 | INTRAOCULAR LENS COMPOSITIONS | ALCON INC (CH) | 2024-02-28 | — | — | EP | disclosed |
| US-11642217-B2 | Intraocular lens compositions | ALCON INC. (CH) | 2023-05-09 | — | — | US | disclosed |
| US-11077057-B2 | Polymer-grafted nanobins | NORTHWESTERN UNIVERSITY (US) | 2021-08-03 | — | — | US | disclosed |
| US-20200405474-A1 | INTRAOCULAR LENS COMPOSITIONS | ALCON RESEARCH, LTD. | 2020-12-31 | — | — | US | disclosed |
| US-10806566-B2 | Intraocular lens compositions | ALCON INC. (CH) | 2020-10-20 | — | — | US | disclosed |
| US-20200155454-A1 | POLYMER-GRAFTED NANOBINS | NORTHWESTERN UNIVERSITY | 2020-05-21 | — | — | US | disclosed |
| EP-3638705-A1 | INTRAOCULAR LENS COMPOSITIONS | ALCON INC. (CH) | 2020-04-22 | — | — | EP | disclosed |
| US-20190091154-A1 | HIGH DENSITY LIPOPROTEIN FUNCTIONALIZED MAGNETIC NANOSTRUCTURES | UNIV NORTHWESTERN (US) | 2019-03-28 | — | — | US | disclosed |
| WO-2018229653-A1 | INTRAOCULAR LENS COMPOSITIONS | NOVARTIS AG (CH) | 2018-12-20 | — | — | WO | disclosed |
| WO-2006105161-A2 | COATED MEDICAL DEVICE | CARTILIX, INC. (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006036681-A2 | CARTILAGE FILLING DEVICE | CARTILIX, INC. (US) | 2006-04-06 | — | — | WO | disclosed |
| CN-1716664-A | Membrane-electrode assembly for fuel cell and fuel cell comprising the same | SAMSUNG SDI CO LTD (KR) | 2006-01-04 | — | — | CN | disclosed |
| WO-2005123903-A2 | CULTURE AID FOR CELLS AND TISSUES | JOHNS HOPKINS UNIVERSITY (US) | 2005-12-29 | — | — | WO | disclosed |
| EP-1558216-A2 | CROSS-LINKED POLYMER MATRICES, AND METHODS OF MAKING AND USING SAME | Johns Hopkins University School of Medicine (US) | 2005-08-03 | — | — | EP | disclosed |
| CN-1577946-A | Polymer electrolyte for rechargeable lithium battery and rechargeable lithium battery comprising same | SAMSUNG SDI CO LTD (KR) | 2005-02-09 | — | — | CN | disclosed |
| WO-2004029137-A2 | CROSS-LINKED POLYMER MATRICES, AND METHODS OF MAKING AND USING SAME | JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (US) | 2004-04-08 | — | — | WO | disclosed |
| US-5888650-A | Temperature-responsive adhesive article | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5508313-A | PRESSURE SENSITIVE ADHESIVES BASED ON UNSATURATED ESTERS AND EITHER ACRYLATED POLYETHERS OR ALKYLENE OXIDES; STERICALLY STABILIZED AGAINEST COAGULATION; COLD RESISTANCE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130116405-A1 | COMPOSITIONS COMPRISING MODIFIED COLLAGEN AND USES THEREFOR | COL1A1, COL2A1, COL14A1 | TSHR 4374/4885TP53 1283/4885EGLN1 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.