SCHEMBL3985477

SCHEMBL3985477

CC(C)(C)OC(=O)Oc1ccc(-c2ccc(Br)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.62
KDM1A O60341 1/20 0.46
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
RECQL P46063 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MAPT P10636 2/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
CA2 P00918 2/20 0.39
HSD17B10 Q99714 1/20 0.39
TP53 P04637 1/20 0.38
MGLL Q99685 1/20 0.38
MCL1 Q07820 1/20 0.38
SLC6A3 Q01959 1/20 0.37
CYP2D6 P10635 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4065322 0.95 ELANE (0.68) ELANEKDM1ARAB9ANPC1RECQL
SCHEMBL4059798 0.91 ELANE (0.72) ELANEKDM1ARAB9AMEN1KMT2A
SCHEMBL978959 0.86 ELANE (0.66) ELANEKDM1ARAB9ANPC1SMN1; SMN2
SCHEMBL919670 0.86 ELANE (0.66) ELANEKDM1ARAB9ANPC1SMN1; SMN2
SCHEMBL9341912 0.85 ELANE (0.57) ELANEKDM1ARAB9ANPC1RECQL
SCHEMBL4061370 0.85 ELANE (0.81) ELANEKDM1ARAB9AMEN1KMT2A
SCHEMBL4060624 0.84 ELANE (0.64) ELANEKDM1ARAB9ANPC1SMN1; SMN2
SCHEMBL1638842 0.83 MEN1 (0.45) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL4058207 0.83 ELANE (0.54) ELANEKDM1ARAB9ANPC1RECQL
SCHEMBL14878467 0.83 ELANE (0.62) ELANEKDM1ARAB9ANPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2061767-A1 ARYLAMINOARYL-ALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, PROCESSES FOR PREPARING THEM, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THEIR USE Sanofi-Aventis (FR) 2009-05-27 EP disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
WO-2008017381-A1 ARYLAMINOARYL-ALKYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, PROCESSES FOR PREPARING THEM, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THEIR USE SANOFI-AVENTIS (FR) 2008-02-14 WO disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed
EP-0391212-B1 Process for preparing bifunctional Z-stilbene compounds, new bifunctional Z-stilbene compounds and their use for preparing polymers BAYER AG (DE) 1994-05-25 EP disclosed
EP-0391212-A2 Process for preparing bifunctional Z-stilbene compounds, new bifunctional Z-stilbene compounds and their use for preparing polymers BAYER AG (DE) 1990-10-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM ELANE 422/4885KDM1A 113/4885RAB9A 2005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.