Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 5/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | PI4KA | P42356 | 1/20 | 0.32 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.32 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | AHCY | P23526 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3981358 | 0.75 | FDPS (0.67) | FDPSADORA2AADORA1FGFR1FGFR4 | |
| SCHEMBL3985727 | 0.74 | FDPS (0.58) | FDPSFGFR1FGFR4HDAC6P2RX7 | |
| SCHEMBL29782733 | 0.71 | CYP3A4 (0.38) | FDPSFGFR1 | |
| SCHEMBL2003351 | 0.71 | ADORA2A (0.44) | FDPSADORA2AADORA2BADORA1FGFR1 | |
| SCHEMBL9683381 | 0.70 | FDPS (0.42) | FDPSFGFR1FGFR4HDAC6P2RX7 | |
| SCHEMBL9683394 | 0.69 | FDPS (0.41) | FDPSFGFR1FGFR4HDAC6P2RX7 | |
| SCHEMBL9417142 | 0.69 | FDPS (0.41) | FDPSFGFR1FGFR4HDAC6P2RX7 | |
| SCHEMBL16617509 | 0.68 | FDPS (0.46) | FDPSFGFR1FGFR4HDAC6P2RX7 | |
| SCHEMBL2475932 | 0.68 | ADORA2A (0.64) | FDPSADORA2AADORA2BADORA1FGFR1 | |
| SCHEMBL31331738 | 0.68 | ADORA2A (0.64) | FDPSADORA2AADORA2BADORA1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | claimed |
| WO-2009056952-A1 | GEMINAL BISPHOSPHONATES, THEIR PREPARATION AND THEIR USE IN THE FIELD OF ONCOLOGY | TETRAPHARM S.R.L. (IT) | 2009-05-07 | — | — | WO | disclosed |