Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683394 | 0.97 | FDPS (0.41) | FDPSHSP90AA1HSP90AB1FGFR1FGFR4 | |
| SCHEMBL9858079 | 0.88 | FDPS (0.40) | FDPSHSP90AA1HSP90AB1FGFR1FGFR4 | |
| SCHEMBL9683747 | 0.86 | ADORA2A (0.43) | FGFR1 | |
| SCHEMBL9417142 | 0.85 | FDPS (0.41) | FDPSHSP90AA1HSP90AB1FGFR1FGFR4 | |
| SCHEMBL9683437 | 0.83 | CYP3A4 (0.43) | FGFR1 | |
| SCHEMBL9684186 | 0.79 | PTK2 (0.33) | PTK2 | |
| SCHEMBL9685074 | 0.76 | PTK2 (0.31) | PTK2 | |
| SCHEMBL9685502 | 0.75 | FDPS (0.34) | FDPSHSP90AA1HSP90AB1 | |
| SCHEMBL16617509 | 0.75 | FDPS (0.46) | FDPSFGFR1FGFR4HDAC6P2RX7 | |
| SCHEMBL9858339 | 0.74 | FGFR1 (0.50) | FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |