Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | POLG | P54098 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 6/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858079 | 0.93 | FDPS (0.40) | FDPSSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9417160 | 0.86 | SLC22A6 (0.50) | SLC22A6ABCB11POLA1POLGFAP | |
| SCHEMBL9683381 | 0.85 | FDPS (0.42) | FDPSFGFR1FGFR4HDAC6P2RX7 | |
| SCHEMBL9683394 | 0.84 | FDPS (0.41) | FDPSFGFR1FGFR4HDAC6P2RX7 | |
| SCHEMBL9858339 | 0.80 | FGFR1 (0.50) | SLC22A6ABCB11POLA1POLGFAP | |
| SCHEMBL9417258 | 0.79 | — | — | |
| SCHEMBL9857669 | 0.78 | ABCB11 (0.36) | FDPSSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9417208 | 0.76 | CDK1 (0.43) | SLC22A6ABCB11POLA1POLGFAP | |
| SCHEMBL9417250 | 0.76 | FDPS (0.37) | FDPSSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9127128 | 0.76 | FAP (0.48) | SLC22A6ABCB11POLA1POLGFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319228-B1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1994-11-02 | — | — | EP | disclosed |
| US-5247085-A | Phosphonate containing purine compounds | BEECHAM GROUP P.L.C. (GB) | 1993-09-21 | — | — | US | disclosed |
| EP-0319228-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1989-06-07 | — | — | EP | disclosed |