Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 4/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.36 |
| ▸ | PARP1 | P09874 | 4/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5535285 | 0.75 | SRC (0.50) | NNMTMAPK8CSNK1A1LIMK1MAP2K1 | |
| SCHEMBL30951795 | 0.75 | SIRT3 (0.41) | NNMTMAPK8CSNK1A1LIMK1MAP2K1 | |
| SCHEMBL30450524 | 0.74 | SIRT3 (0.43) | NNMTSIRT3TDP1CYP11B2PARP1 | |
| Hydrochloric Acid SCHEMBL21331756 | 0.73 | NNMT (0.37) | NNMTPARP1SRCSIGMAR1 | |
| SCHEMBL27098457 | 0.70 | UHRF1 (0.37) | NNMTTDP1CYP11B2SRCKDM4E | |
| SCHEMBL9175188 | 0.69 | NNMT (0.51) | NNMTMAPK8CSNK1A1LIMK1MAP2K1 | |
| SCHEMBL30951792 | 0.68 | SIRT3 (0.41) | NNMTMAPK8CSNK1A1LIMK1MAP2K1 | |
| SCHEMBL25450371 | 0.67 | SIGMAR1 (0.33) | NNMTTDP1SIGMAR1 | |
| SCHEMBL25787747 | 0.67 | NNMT (1.00) | NNMTCYP11B2KDM4EMAPT | |
| SCHEMBL9175444 | 0.65 | KDM4E (0.43) | NNMTMAPK8CSNK1A1LIMK1PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056556-A1 | SUBSTITUTE 1, 6-NAPHTHYRIDINES FOR USE AS SCD INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-05-07 | — | — | WO | claimed |