Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 6/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3983379 | 1.00 | HRH3 (0.32) | HRH3HTR4USP2ALDH1A1LMNA | |
| SCHEMBL1022505 | 0.90 | HTR4 (0.37) | HTR4 | |
| SCHEMBL1021565 | 0.90 | HTR4 (0.37) | HTR4 | |
| SCHEMBL2980596 | 0.90 | HTR4 (0.37) | HTR4 | |
| SCHEMBL1022503 | 0.90 | HTR4 (0.37) | HTR4 | |
| SCHEMBL3983380 | 0.87 | KDM4E (0.38) | USP2ALDH1A1LMNA | |
| SCHEMBL3986069 | 0.87 | KDM4E (0.38) | USP2ALDH1A1LMNA | |
| SCHEMBL2975908 | 0.84 | PIK3CD (0.37) | USP2ALDH1A1 | |
| SCHEMBL2975909 | 0.84 | PIK3CD (0.37) | USP2ALDH1A1 | |
| SCHEMBL2965770 | 0.84 | PIK3CD (0.37) | USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1807423-B1 | QUINOLINONE-CARBOXAMIDE COMPOUNDS | THERAVANCE INC (US) | 2009-05-20 | — | — | EP | disclosed |