Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986119 | 1.00 | KMT2A (0.35) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL732858 | 0.74 | KMT2A (0.37) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL4512434 | 0.72 | KMT2A (0.38) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL34463705 | 0.72 | KMT2A (0.38) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL19609005 | 0.70 | PIK3CA (0.39) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL4826623 | 0.69 | KMT2A (0.33) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL19608988 | 0.68 | EGFR (0.39) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL25135417 | 0.67 | PKM (0.48) | KMT2AKDM4EMEN1ALDH1A1PKM | |
| SCHEMBL3986117 | 0.65 | KMT2A (0.35) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL4496272 | 0.65 | ALKBH5 (0.34) | CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2027125-A1 | PENTACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2009-02-25 | — | — | EP | claimed |
| WO-2007129119-A1 | PENTACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2007-11-15 | — | — | WO | claimed |