SCHEMBL398659

SCHEMBL398659

CCc1ccc(-c2nnc(-c3ccc(CC)c(CC)c3N)o2)c(N)c1CC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATR Q13535 2/20 0.36
▸ RAB9A P51151 9/20 0.35
▸ NPC1 O15118 8/20 0.35
▸ SMN1; SMN2 Q16637 8/20 0.35
▸ CASP3 P42574 1/20 0.35
▸ SENP8 Q96LD8 1/20 0.35
▸ SENP7 Q9BQF6 1/20 0.35
▸ SENP6 Q9GZR1 1/20 0.35
▸ ALDH1A1 P00352 6/20 0.33
▸ HPGD P15428 6/20 0.33
▸ KDM4E B2RXH2 5/20 0.33
▸ GAA P10253 2/20 0.33
▸ CA1 P00915 1/20 0.32
▸ CA2 P00918 1/20 0.32
▸ LMNA P02545 2/20 0.32
▸ S1PR1 P21453 2/20 0.32
▸ ALOX15 P16050 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ GLA P06280 1/20 0.32
▸ HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2951052 0.81 NOTUM (0.41) RAB9ANPC1SMN1; SMN2ALDH1A1KDM4E
SCHEMBL1794969 0.75 NPC1 (0.38) ATRRAB9ANPC1SMN1; SMN2CASP3
SCHEMBL1960607 0.74 ALDH1A1 (0.46) RAB9ANPC1SMN1; SMN2CASP3SENP7
SCHEMBL393531 0.72 POLB (0.35) ALDH1A1KDM4EHTTMAPTPOLB
Methane SCHEMBL27970424 0.72 ALDH1A1 (0.45) RAB9ANPC1SMN1; SMN2CASP3SENP7
SCHEMBL1647070 0.71 MAPT (0.41) RAB9ASMN1; SMN2ALDH1A1KDM4EMAPT
SCHEMBL571458 0.69 POLB (0.40) ALDH1A1HTTMAPTPOLBCTRC
SCHEMBL3674137 0.69 GABRA1 (0.36) ALDH1A1GAAMAPK1HTTMAPT
SCHEMBL4253508 0.68 NPC1 (0.35) RAB9ANPC1SMN1; SMN2CASP3SENP8
SCHEMBL5697401 0.67 NOS3 (0.41) RAB9ANPC1SMN1; SMN2CASP3SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956793-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-02-17 — — US disclosed
US-8859173-B2 Electrophotographic photoreceptor, process cartridge, image forming apparatus, cured film, and organic electroluminescent device FUJI XEROX CO., LTD. (JP) 2014-10-14 — — US disclosed
US-8808953-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-08-19 — — US disclosed
US-20130252147-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-09-26 — — US disclosed
US-20130236821-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-09-12 — — US disclosed
US-8518617-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2013-08-27 — — US disclosed
US-8103191-B2 Image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-01-24 — — US disclosed
US-20110207039-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, IMAGE FORMING APPARATUS, CURED FILM, AND ORGANIC ELECTROLUMINESCENT DEVICE FUJI XEROX CO., LTD. (JP) 2011-08-25 — — US disclosed
US-20110207041-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2011-08-25 — — US disclosed
US-7561828-B2 Image-forming apparatus including an electrophotographic photoreceptor having an undercoat layer FUJI XEROX CO., LTD. (JP) 2009-07-14 — — US disclosed
US-20090010664-A1 IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2009-01-08 — — US disclosed
US-20060013615-A1 Image-forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2006-01-19 — — US disclosed
US-4427753-A Electrophotographic photosensitive member with disazo or trisazo compound CANON KABUSHIKI KAISHA (JP) 1984-01-24 — — US disclosed
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