SCHEMBL3987095

SCHEMBL3987095

O=C1CCN(c2cccc(Cl)c2)N1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 18/20 1.00
G6PD P11413 1/20 0.66
ALOX15 P16050 1/20 0.66
ALOX12 P18054 1/20 0.66
PTGS1 P23219 1/20 0.66
PTGS2 P35354 1/20 0.66
ALDH1A1 P00352 2/20 0.52
MAPT P10636 2/20 0.52
HPGD P15428 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
GAA P10253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9644532 0.90 ALOX5 (1.00) ALOX5G6PDALOX15ALOX12PTGS1
SCHEMBL7536266 0.81 ALOX5 (1.00) ALOX5G6PDALOX15ALOX12PTGS1
SCHEMBL31021948 0.81 ALOX5 (0.82) ALOX5G6PDALOX15ALOX12PTGS1
SCHEMBL28816190 0.81 ALOX5 (0.82) ALOX5G6PDALOX15ALOX12PTGS1
SCHEMBL10947701 0.81 ALOX5 (0.82) ALOX5G6PDALOX15ALOX12PTGS1
SCHEMBL2379976 0.80 ALOX5 (1.00) ALOX5G6PDALOX15ALOX12PTGS1
Phenidone SCHEMBL235192 0.80 ALOX5 (1.00) ALOX5G6PDALOX15ALOX12PTGS1
Phenidone SCHEMBL10904906 0.80 ALOX5 (1.00) ALOX5G6PDALOX15ALOX12PTGS1
SCHEMBL7094594 0.79 ALOX5 (0.67) ALOX5G6PDALOX15ALOX12PTGS1
SCHEMBL7095931 0.79 ALOX5 (0.66) ALOX5G6PDALOX15ALOX12PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114874144-B Process for preparing 4-bromo-N-arylpyrazole compound 曲靖师范学院 2024-07-05 CN claimed
US-4423139-A SYNERGISTIC MIXTURE OF AROMATIC POLYOL, AROMATIC DIAMINE, OR AROMATIC OXYAMINE WITH 1-PHENYL-3-PYRAZOLIDINONE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1983-12-27 US claimed
EP-3112350-B1 METHOD FOR PRODUCING PYRAZOLE COMPOUND SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9624177-B2 Method for producing pyrazole compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-04-18 US disclosed
US-20170008853-A1 METHOD FOR PRODUCING PYRAZOLE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-01-12 US disclosed
EP-3112350-A1 METHOD FOR PRODUCING PYRAZOLE COMPOUND Sumitomo Chemical Company, Limited (JP) 2017-01-04 EP disclosed
WO-2007117778-A9 QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS KALYPSYS INC (US) 2009-05-22 WO disclosed
EP-1986747-A2 QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS Kalypsys, Inc. (US) 2008-11-05 EP disclosed
US-20080139558-A1 QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS KALYPSYS, INC. (US) 2008-06-12 US disclosed
WO-2007117778-A2 QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS KALYPSYS, INC. (US) 2007-10-18 WO disclosed
US-4916044-A STORAGE STABLE, SHARP IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1990-04-10 US disclosed
US-4201578-A HYDROQUINONE ESTERS EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4199354-A BALLASTED IMAGE-DYE PROVIDING MATERIALS EASTMAN KODAK COMPANY (US) 1980-04-22 US disclosed
US-4199355-A BALLASTED CHROMOGENS EASTMAN KODAK COMPANY (US) 1980-04-22 US disclosed
US-4192678-A DIFFUSION TRANSFER, COLOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1980-03-11 US disclosed
US-4192679-A DEVELOPER-SCAVENGER EASTMAN KODAK COMPANY (US) 1980-03-11 US disclosed
US-4139379-A Photographic elements containing ballasted electron-accepting nucleophilic displacement compounds EASTMAN KODAK COMPANY (US) 1979-02-13 US disclosed
US-4126461-A NONDIFFUSIBLE RESORCINOL COUPLER EASTMAN KODAK COMPANY (US) 1978-11-21 US disclosed
US-4108850-A Positive-working immobile photographic azo compounds EASTMAN KODAK COMPANY (US) 1978-08-22 US disclosed
US-3980479-A Positive-working immobile photographic compounds which cleave by intramolecular nucleophilic displacement in alkali unless oxidized EASTMAN KODAK COMPANY (US) 1976-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008853-A1 METHOD FOR PRODUCING PYRAZOLE COMPOUND CBR3, POR, CBR1 ALOX5 538/4885G6PD 210/4885ALOX15 574/4885
US-20080139558-A1 QUINOLONES USEFUL AS INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITORS NOS2, NOS1, NQO2 ALOX5 318/4885G6PD 63/4885ALOX15 369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.