Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300990 | 0.94 | TSHR (0.50) | TSHRHPGDUSP2ALDH1A1GAA | |
| SCHEMBL10798080 | 0.87 | TSHR (0.48) | TSHRHPGDUSP2ALDH1A1GAA | |
| SCHEMBL250536 | 0.86 | TSHR (0.47) | TSHRHPGDUSP2ALDH1A1GAA | |
| SCHEMBL27511455 | 0.86 | TSHR (0.68) | TSHRHPGDUSP2ALDH1A1GAA | |
| SCHEMBL398716 | 0.86 | TSHR (0.47) | TSHRHPGDUSP2ALDH1A1GAA | |
| SCHEMBL22081599 | 0.82 | TSHR (0.48) | TSHRHPGDUSP2ALDH1A1GAA | |
| SCHEMBL11420568 | 0.82 | TSHR (0.38) | TSHRHPGDALDH1A1GAAGABRA1 | |
| SCHEMBL24781618 | 0.81 | P2RX7 (0.44) | TSHRRORCHTR2CHTR2BAR | |
| SCHEMBL20621249 | 0.81 | TSHR (0.43) | TSHRHPGDUSP2ALDH1A1GAA | |
| Methane SCHEMBL28472323 | 0.80 | TSHR (0.46) | TSHRALDH1A1PKMHSD17B10GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022097609-A1 | 9,9-BIS (3,5-DIALKYL-4-AMINOPHENYL) FLUORENE COMPOUND PRODUCTION METHOD | 東レ・ファインケミカル株式会社 | 2022-05-12 | — | — | WO | disclosed |
| EP-0492473-A1 | Process for the preparation of 4-substituted 2,6-dialkylanilines | LONZA AG (CH) | 1992-07-01 | — | — | EP | disclosed |
| US-4289906-A | Chemical process for preparing methylene bis-anilines | ETHYL CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |
| US-4194008-A | INSECTICIDE, FUNGICIDE, MITICIDE, PARASITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-18 | — | — | US | disclosed |
| US-4173645-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-06 | — | — | US | disclosed |
| EP-0000365-A1 | N-aryl-N'-alcoyl-S-alcoyl isothioureas, process for their preparation and their use against animal and vegetal pests | BAYER AG (DE) | 1979-01-24 | — | — | EP | disclosed |
| US-3983174-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |