SCHEMBL770339

SCHEMBL770339

CCc1cccc(C(C)C)c1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 7/20 0.42
GABRG2 P18507 2/20 0.42
GABRB3 P28472 2/20 0.42
GABRB2 P47870 6/20 0.41
FAAH O00519 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
GABRB1 P18505 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2C P28335 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
HTR2B P41595 1/20 0.41
GABRA2 P47869 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29631719 1.00 GABRA1 (0.42) GABRA1GABRG2GABRB3GABRB2FAAH
SCHEMBL14647742 0.88 GABRA1 (0.43) GABRA1GABRG2GABRB3GABRB2FAAH
SCHEMBL5575889 0.85 GABRA1 (0.43) GABRA1GABRG2GABRB3GABRB2FAAH
SCHEMBL3962423 0.84 GABRA1 (0.39) GABRA1GABRG2GABRB3GABRB2FAAH
SCHEMBL398716 0.84 TSHR (0.47) GABRA1GABRB2HPGDTSHRHTT
Propane SCHEMBL27557470 0.82 GABRA1 (0.48) GABRA1GABRG2GABRB3GABRB2FAAH
SCHEMBL6313117 0.82 GABRA1 (0.40) GABRA1GABRB2TSHRHTTELANE
SCHEMBL22415013 0.82 GABRA1 (0.50) GABRA1GABRG2GABRB3GABRB2FAAH
SCHEMBL27429992 0.82 GABRA1 (0.41) GABRA1GABRG2GABRB3GABRB2FAAH
SCHEMBL3962086 0.81 SOAT1 (0.39) GABRA1GABRG2GABRB3GABRB2FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0479943-A4 ADHESIVES AND METHOD FOR MAKING SAME 1992-09-16 EP claimed
EP-0479943-A1 ADHESIVES AND METHOD FOR MAKING SAME MARTIN MARIETTA ENERGY SYSTEMS, INC. (US) 1992-04-15 EP claimed
WO-1991000308-A1 ADHESIVES AND METHOD FOR MAKING SAME MARTIN MARIETTA ENERGY SYSTEMS, INC. (US) 1991-01-10 WO claimed
EP-4543894-A1 NOVEL RUTHENIUM COMPLEXES, METHOD OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS USED IN THIS METHOD, METHOD OF THEIR SYNTHESIS AND THE USE OF NOVEL RUTHENIUM COMPLEXES IN OLEFIN METATHESIS REACTIONS Uniwersytet Warszawski (PL) 2025-04-30 EP disclosed
CN-118974107-A Maleimide compound, curable resin composition, cured product thereof, amine compound, and reactant of amine compound and maleic anhydride 日本化药株式会社 2024-11-15 CN disclosed
US-12054578-B2 Process for producing porous materials AEROGEL-IT GMBH (DE) 2024-08-06 US disclosed
CN-113260646-B Aromatic amine resin, maleimide resin, curable resin composition, and cured product thereof 日本化药株式会社 2024-04-02 CN disclosed
WO-2023248205-A1 NOVEL RUTHENIUM COMPLEXES, METHOD OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS USED IN THIS METHOD, METHOD OF THEIR SYNTHESIS AND THE USE OF NOVEL RUTHENIUM COMPLEXES IN OLEFIN METATHESIS REACTIONS UNIWERSYTET WARSZAWSKI (PL) 2023-12-28 WO disclosed
WO-2023189411-A1 MALEIMIDE COMPOUND, CURABLE RESIN COMPOSITION AND CURED PRODUCT THEREOF, AMINE COMPOUND AND REACTION PRODUCT OF AMINE COMPOUND WITH MALEIC ANHYDRIDE 日本化薬株式会社 2023-10-05 WO disclosed
US-11766436-B2 KRAS G12C inhibitors and methods of using the same AMGEN INC. (US) 2023-09-26 US disclosed
US-20230255101-A1 Tetradentate Metal Complexes with Carbon Group Bridging Ligands UNIV ARIZONA STATE (US) 2023-08-10 US disclosed
EP-0055363-B1 PERYLENE TETRACARBOXYLIC-ACID DIIMIDES AND THEIR USE BASF Aktiengesellschaft (DE) 1983-12-14 EP disclosed
US-4401833-A Process for the preparation of 4-chloro-2,6-dialkylanilines BAYER AKTIENGESELLSCHAFT (DE) 1983-08-30 US disclosed
EP-0068138-A1 Chloroacetanilide, process for its preparation and herbicidal agents containing it HOECHST AKTIENGESELLSCHAFT (DE) 1983-01-05 EP disclosed
EP-0055363-A1 Perylene tetracarboxylic-acid diimides and their use BASF Aktiengesellschaft (DE) 1982-07-07 EP disclosed
EP-0052817-A1 Process for the preparation of 4-chloro-2,6 dialkyl anilines BAYER AG (DE) 1982-06-02 EP disclosed
US-4289906-A Chemical process for preparing methylene bis-anilines ETHYL CORPORATION (US) 1981-09-15 US disclosed
US-4194008-A INSECTICIDE, FUNGICIDE, MITICIDE, PARASITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-03-18 US disclosed
EP-0003101-A1 Substituted N-cyclohexyl isothiourea, their preparation and their use as pesticides BAYER AG (DE) 1979-07-25 EP disclosed
EP-0000365-A1 N-aryl-N'-alcoyl-S-alcoyl isothioureas, process for their preparation and their use against animal and vegetal pests BAYER AG (DE) 1979-01-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230255101-A1 Tetradentate Metal Complexes with Carbon Group Bridging Ligands STAU1, POLR1G, CLTC GABRA1 1810/4885GABRG2 2094/4885GABRB3 1319/4885
US-11766436-B2 KRAS G12C inhibitors and methods of using the same KRAS, NRAS, HRAS GABRA1 4420/4885GABRG2 2943/4885GABRB3 4532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.