Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918872 | 1.00 | NFKB1 (0.33) | NFKB1NFKB2RELA | |
| SCHEMBL1648671 | 0.83 | NFKB1 (0.34) | NFKB1NFKB2RELA | |
| SCHEMBL31473481 | 0.80 | SLC2A1 (0.37) | NFKB1NFKB2RELA | |
| SCHEMBL3192675 | 0.77 | NFKB1 (0.42) | NFKB1NFKB2RELA | |
| Water SCHEMBL5170044 | 0.76 | NFKB1 (0.41) | NFKB1NFKB2RELA | |
| SCHEMBL17918196 | 0.75 | NFKB1 (0.39) | NFKB1NFKB2RELA | |
| SCHEMBL4790845 | 0.75 | — | — | |
| SCHEMBL4911808 | 0.75 | — | — | |
| SCHEMBL31473482 | 0.74 | — | — | |
| SCHEMBL3983475 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138485-A1 | Chemical synthons and intermediates | PURDUE RESEARCH FOUNDATION | 2004-07-15 | — | — | US | claimed |
| US-7501535-B2 | Chemical synthons and intermediates | PURDUE RESEARCH FOUNDATION (US) | 2009-03-10 | — | — | US | disclosed |
| US-20040138485-A1 | Chemical synthons and intermediates | PURDUE RESEARCH FOUNDATION | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138485-A1 | Chemical synthons and intermediates | STS, TST, CBS | NFKB1 4695/4885NFKB2 4646/4885RELA 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.