Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 7/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980836 | 0.82 | PTGDR2 (0.51) | CHRM1MPORORCKLKB1PTGDR2 | |
| SCHEMBL3982787 | 0.81 | PTGDR2 (0.42) | CHRM1RORCKLKB1TNIKPTGDR2 | |
| SCHEMBL3986238 | 0.79 | MAPKAPK2 (0.38) | KMT2AALDH1A1 | |
| SCHEMBL3988868 | 0.74 | MPO (0.48) | CHRM1MPORORCKLKB1KMT2A | |
| SCHEMBL2570703 | 0.71 | PTGDR2 (0.46) | MPORORCTNIKPTGDR2 | |
| SCHEMBL2576178 | 0.70 | PTGDR2 (0.41) | CHRM1MPORORCTNIKKDM4E | |
| SCHEMBL2573787 | 0.70 | RORC (0.42) | CHRM1RORCKDM4EALDH1A1MAPK1 | |
| SCHEMBL2570635 | 0.69 | RORC (0.37) | MPORORCPTGDR2 | |
| SCHEMBL2568510 | 0.69 | PTGDR2 (0.46) | MPORORCTNIKPTGDR2 | |
| SCHEMBL2572989 | 0.69 | PTGDR2 (0.44) | CHRM1MPORORCTNIKKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |