Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 8/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980836 | 0.91 | PTGDR2 (0.51) | PTGDR2KLKB1CHRM1RXFP1RORC | |
| SCHEMBL3989733 | 0.83 | LMNA (0.39) | PTGDR2RXFP1 | |
| SCHEMBL3989030 | 0.81 | CHRM1 (0.39) | PTGDR2KLKB1CHRM1RORCTNIK | |
| SCHEMBL3351455 | 0.77 | PTGDR2 (0.43) | PTGDR2KLKB1CHRM1RORC | |
| SCHEMBL2571339 | 0.77 | PTGDR2 (0.50) | PTGDR2CHRM1RORC | |
| SCHEMBL2576335 | 0.77 | PTGDR2 (0.43) | PTGDR2KLKB1CHRM1RORC | |
| SCHEMBL2575061 | 0.77 | PTGDR2 (0.56) | PTGDR2RORCADRA2BPPARGPPARD | |
| SCHEMBL2568427 | 0.77 | RORC (0.48) | PTGDR2RORCADRA2BPPARGPPARD | |
| SCHEMBL3345117 | 0.77 | PTGDR2 (0.50) | PTGDR2KLKB1CHRM1RORC | |
| SCHEMBL2570536 | 0.76 | PTGDR2 (0.56) | PTGDR2KLKB1CHRM1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |