Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3991157 | 0.81 | HSD11B1 (0.32) | — | |
| SCHEMBL2752156 | 0.77 | SLC6A2 (0.33) | — | |
| SCHEMBL3995451 | 0.76 | DRD1 (0.36) | — | |
| SCHEMBL2750808 | 0.75 | TSHR (0.31) | TSHRSMN1; SMN2 | |
| SCHEMBL3995208 | 0.74 | RXRA (0.36) | TSHRSMN1; SMN2 | |
| SCHEMBL3996017 | 0.74 | CES2 (0.34) | TSHRSMN1; SMN2 | |
| SCHEMBL6155275 | 0.73 | MAPT (0.50) | — | |
| SCHEMBL3988351 | 0.72 | TSHR (0.36) | TSHRSMN1; SMN2 | |
| SCHEMBL2750381 | 0.72 | TSHR (0.33) | NFE2L2TSHRSMN1; SMN2 | |
| SCHEMBL3991015 | 0.72 | MAPT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066643-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-10 | — | — | EP | disclosed |
| EP-2064190-A1 | PYRIMIDYLMETHYL-SULFONAMIDE COMPOUNDS USEFUL AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008062011-A1 | PYRIMIDYLMETHYL-SULFONAMIDE COMPOUNDS USEFUL AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008062012-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |