Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7774674 | 0.88 | ALDH1A1 (0.56) | LMNAALDH1A1TSHRCA12CA14 | |
| SCHEMBL1439008 | 0.82 | MGAM (0.45) | ALDH1A1TSHRKMT2ASMN1; SMN2MAPT | |
| SCHEMBL30987140 | 0.82 | LMNA (0.58) | LMNAALDH1A1TSHRCA12CA14 | |
| SCHEMBL23521793 | 0.81 | ALDH1A1 (0.38) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL72889 | 0.79 | TSHR (0.67) | LMNAALDH1A1TSHRCA12CA14 | |
| SCHEMBL713525 | 0.78 | — | — | |
| SCHEMBL7770641 | 0.77 | TSHR (0.47) | LMNAALDH1A1TSHREPHX2SMN1; SMN2 | |
| SCHEMBL12847508 | 0.77 | TSHR (0.63) | LMNAALDH1A1TSHRCA12CA14 | |
| SCHEMBL10042464 | 0.77 | TSHR (0.63) | LMNAALDH1A1TSHRCA12CA14 | |
| Hydrochloric Acid SCHEMBL929671 | 0.77 | LMNA (0.47) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116148398-B | Method for detecting trace chemical hazard in fat-rich food | 北京市疾病预防控制中心 | 2023-09-05 | — | — | CN | claimed |
| CN-116148398-A | Method for detecting trace chemical hazard in fat-rich food | 北京市疾病预防控制中心 | 2023-05-23 | — | — | CN | claimed |
| CN-115216073-B | Oil-resistant corrosion-resistant shore power cable sheath material and preparation method thereof | 广东安拓普聚合物科技有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-115216073-A | Oil-resistant corrosion-resistant shore power cable sheath material and preparation method thereof | 广东安拓普聚合物科技有限公司 | 2022-10-21 | — | — | CN | claimed |
| CN-116148398-B | Method for detecting trace chemical hazard in fat-rich food | 北京市疾病预防控制中心 | 2023-09-05 | — | — | CN | disclosed |
| CN-116148398-A | Method for detecting trace chemical hazard in fat-rich food | 北京市疾病预防控制中心 | 2023-05-23 | — | — | CN | disclosed |
| CN-115216073-B | Oil-resistant corrosion-resistant shore power cable sheath material and preparation method thereof | 广东安拓普聚合物科技有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-115216073-A | Oil-resistant corrosion-resistant shore power cable sheath material and preparation method thereof | 广东安拓普聚合物科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| US-20090291938-A1 | POLO-LIKE KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
| WO-2009067547-A1 | POLO-LIKE KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-05-28 | — | — | WO | disclosed |
| EP-1064254-B1 | ALIPHATIC AMINO CARBOXYLIC AND AMINO PHOSPHONIC ACIDS, AMINO NITRILES AND AMINO TETRAZOLES AS CELLULAR RESCUE AGENTS | UNIV SASKATCHEWAN (CA) | 2007-10-17 | — | — | EP | disclosed |
| US-6984754-B1 | Aliphatic amino carboxylic and amino phosphonic acids amino nitriles and amino tetrazoles as cellular rescue agents | UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. (CA) | 2006-01-10 | — | — | US | disclosed |
| WO-1999048858-A2 | ALIPHATIC AMINO CARBOXYLIC AND AMINO PHOSPHONIC ACIDS, AMINO NITRILES AND AMINO TETRAZOLES AS CELLULAR RESCUE AGENTS | UNIVERSITY OF SASKATCHEWAN TECHNOLOGIES INC. (CA) | 1999-09-30 | — | — | WO | disclosed |
| US-5773508-A | BIODEGRADABLE POLYMER OF ADDITION COPOLYMERS FOR PROTECTIVE COATINGS | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| WO-1997020964-A1 | COMPOSITION AND PROCESS FOR ZINC PHOSPHATE CONVERSION COATING | HENKEL CORPORATION (US) | 1997-06-12 | — | — | WO | disclosed |
| EP-0711813-A2 | Coating varnish composition and antifouling coating composition | Hitachi Chemical Co., Ltd. (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0018549-B1 | TETRAHYDROISOQUINOLINE COMPOUNDS, PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Tanabe Seiyaku Co., Ltd. (JP) | 1981-12-30 | — | — | EP | disclosed |
| US-4294832-A | HYPOTENSIVE AGENTS, ANGIOTENSIN INHIBITORS | TANABE SEIYAKU CO., LTD. (JP) | 1981-10-13 | — | — | US | disclosed |
| EP-0018549-A2 | Tetrahydroisoquinoline compounds, process for preparing them and pharmaceutical compositions containing them | Tanabe Seiyaku Co., Ltd. (JP) | 1980-11-12 | — | — | EP | disclosed |
| US-4025550-A | Derivatives of triiodo-aminobenzenecarboxylic acids and the preparation thereof | CHEMIE LINZ AKTIENGESELLSCHAFT (OE) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291938-A1 | POLO-LIKE KINASE INHIBITORS | PLK1, PLK2, POLK | LMNA 1422/4885ALDH1A1 4009/4885TSHR 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.