SCHEMBL3989205

SCHEMBL3989205

NC(=O)C1CC(c2ccccc2)=NO1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.69
CA2 P00918 4/20 0.69
POLB P06746 3/20 0.58
APAF1 O14727 1/20 0.58
GRK2 P25098 1/20 0.58
APOBEC3G Q9HC16 1/20 0.58
LMNA P02545 3/20 0.51
NPC1 O15118 1/20 0.51
USP2 O75604 1/20 0.51
ALDH1A1 P00352 1/20 0.51
ESR1 P03372 1/20 0.51
RAB9A P51151 1/20 0.51
F10 P00742 2/20 0.51
MIF P14174 2/20 0.50
PDE4A P27815 1/20 0.49
PDE4B Q07343 1/20 0.49
PDE4C Q08493 1/20 0.49
PDE4D Q08499 1/20 0.49
MAPT P10636 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7451017 0.88 POLB (0.73) CA1CA2POLBAPAF1GRK2
SCHEMBL3981403 0.87 LMNA (0.56) CA1CA2POLBAPAF1GRK2
SCHEMBL3989190 0.87 CA1 (0.58) CA1CA2POLBAPAF1GRK2
SCHEMBL29846707 0.85 CA1 (0.53) CA1CA2POLBAPAF1GRK2
SCHEMBL24517994 0.85 POLB (0.74) CA1CA2POLBAPAF1GRK2
SCHEMBL2674041 0.85 POLB (0.53) CA1CA2POLBAPAF1GRK2
SCHEMBL28965231 0.85 CA1 (0.68) CA1CA2POLBAPAF1GRK2
SCHEMBL3981863 0.85 POLB (0.56) CA1CA2POLBAPAF1GRK2
SCHEMBL12807092 0.85 CA1 (0.59) CA1CA2POLBAPAF1GRK2
SCHEMBL17323274 0.85 CA1 (0.68) CA1CA2POLBAPAF1GRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12319664-B2 Herbicidally active 3-phenylisoxazoline-5-carboxamides of cyclopentenylcarboxylic acid derivatives BAYER AKTIENGESELLSCHAFT (DE) 2025-06-03 US claimed
US-12185723-B2 Herbicidally active 3-phenylisoxazoline-5-carboxamides of s-containing cyclopentenylcarboxylic esters BAYER AKTIENGESELLSCHAFT (DE) 2025-01-07 US claimed
CN-110770232-B Herbicidal 3-phenylisoxazoline-5-carboxamides of tetrahydro-and dihydrofuran carboxylic acids and esters 拜耳公司 2023-08-15 CN claimed
CN-113631038-B Herbicidal 3-phenylisoxazoline-5-carboxamides containing S-cyclopentenyl carboxylic acid esters 拜耳公司 2023-06-30 CN claimed
EP-3937637-B1 HERBICIDAL 3-PHENYLISOXAZOLIN-5-CARBOXAMIDES OF S-CONTAINING CYCLOPENTENYL CARBOXYLIC ACID ESTERS BAYER AG (DE) 2023-04-19 EP claimed
US-11613522-B2 Herbicidally active 3-phenylisoxazoline-5-carboxamides of tetrahydro- and dihydrofurancarboxamides BAYER AKTIENGESELLSCHAFT (DE) 2023-03-28 US claimed
US-11597724-B2 Herbicidally active 3-phenylisoxazoline-5-carboxamides of tetrahydro and dihydrofuran carboxylic acids and esters BAYER AKTIENGESELLSCHAFT (DE) 2023-03-07 US claimed
EP-3743411-B1 HERBICIDAL 3-PHENYLISOXAZOLIN-5-CARBOXAMIDES OF CYCLOPENTENYL CARBOXYLIC ACID DERIVATIVES BAYER AG (DE) 2022-12-21 EP claimed
EP-3937637-A1 HERBICIDALLY ACTIVE 3-PHENYLISOXAZOLINE-5-CARBOXAMIDES OF S-CONTAINING CYCLOPENTENYL CARBOXYLIC ACID ESTERS Bayer Aktiengesellschaft (DE) 2022-01-19 EP claimed
CN-113631038-A Herbicidally active 3-phenylisoxazoline-5-carboxamides containing S-cyclopentenylcarboxylates 拜耳公司 2021-11-09 CN claimed
EP-2900644-A1 HERBICIDAL AND FUNGICIDAL 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLINE-5-CARBOXAMIDES AND 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLINE-5-THIOAMIDES Bayer CropScience AG (DE) 2015-08-05 EP claimed
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP claimed
US-9078442-B2 Herbicidally and fungicidally active 3-phenylisoxazoline-5-carboxamides and 3-phenylisoxazoline-5-thioamides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-07-14 US claimed
US-20140100108-A1 HERBICIDALLY AND FUNGICIDALLY ACTIVE 3-PHENYLISOXAZOLINE-5-CARBOXAMIDES AND 3-PHENYLISOXAZOLINE-5-THIOAMIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-04-10 US claimed
EP-2691379-A1 HERBICIDALLY AND FUNGICIDALLY ACTIVE 3-PHENYLISOXAZOLINE-5-CARBOXAMIDES AND 3-PHENYLISOXAZOLINE-5-THIOAMIDES Bayer Intellectual Property GmbH (DE) 2014-02-05 EP claimed
WO-2012130798-A1 HERBICIDALLY AND FUNGICIDALLY ACTIVE 3-PHNEYLISOXAZOLINE-5-CARBOXAMIDES AND 3-PHNEYLISOXAZOLINE-5-THIOAMIDES BAYER CROPSCIENCE AG (DE) 2012-10-04 WO claimed
US-20090298806-A1 FACTOR XA INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. 2009-12-03 US claimed
EP-1893572-A2 FACTOR XA INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. (US) 2008-03-05 EP claimed
US-20060100193-A1 5-Chloro-N-((1-(4-(2-oxopyridin-1(2H)-yl)phenyl)-1H-1,2,3-triazol-4-yl)methyl)thiophene-2-carboxamide; 5-Chloro-thiophene-2-carboxylic acid (3-p-tolyl-4,5-dihydro-isoxazol-5-ylmethyl)-amide; undesirable thrombosis inhibitor MILLENNIUM PHARMACEUTICALS, INC. (US) 2006-05-11 US claimed
WO-2006002099-A2 FACTOR XA INHIBITORS MILLENNIUM PHARMACEUTICALS, INC. (US) 2006-01-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060100193-A1 5-Chloro-N-((1-(4-(2-oxopyridin-1(2H)-yl)phenyl)-1H-1,2,3-triazol-4-yl)methyl)thiophene-2-carboxamide; 5-Chloro-thiophene-2-carboxylic acid (3-p-tolyl-4,5-dihydro-isoxazol-5-ylmethyl)-amide; undesirable thrombosis inhibitor TFPI, TFPI2, F12 CA1 412/4885CA2 348/4885POLB 3327/4885
US-11597724-B2 Herbicidally active 3-phenylisoxazoline-5-carboxamides of tetrahydro and dihydrofuran carboxylic acids and esters AADAC, DDT, DPP7 CA1 470/4885CA2 199/4885POLB 3906/4885
US-20090298806-A1 FACTOR XA INHIBITORS TFPI, F12, F11 CA1 246/4885CA2 698/4885POLB 3172/4885
US-11613522-B2 Herbicidally active 3-phenylisoxazoline-5-carboxamides of tetrahydro- and dihydrofurancarboxamides AADAC, DDT, CBR3 CA1 511/4885CA2 224/4885POLB 3475/4885
US-12319664-B2 Herbicidally active 3-phenylisoxazoline-5-carboxamides of cyclopentenylcarboxylic acid derivatives AADAC, PRDX5, DDT CA1 671/4885CA2 116/4885POLB 3525/4885
US-20140100108-A1 HERBICIDALLY AND FUNGICIDALLY ACTIVE 3-PHENYLISOXAZOLINE-5-CARBOXAMIDES AND 3-PHENYLISOXAZOLINE-5-THIOAMIDES CYP4X1, PRDX4, PRDX2 CA1 802/4885CA2 90/4885POLB 3743/4885
US-12185723-B2 Herbicidally active 3-phenylisoxazoline-5-carboxamides of s-containing cyclopentenylcarboxylic esters NOTUM, AADAC, DDT CA1 957/4885CA2 354/4885POLB 3409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.