SCHEMBL3989288

SCHEMBL3989288

CCCCCCCCCCCCCCCCC1(C(N)=O)Cc2cccc(c2)C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK2 Q9NRA0 1/20 0.39
SPHK1 Q9NYA1 1/20 0.39
CETP P11597 3/20 0.39
SCN5A Q14524 3/20 0.36
SCN9A Q15858 3/20 0.36
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 1/20 0.36
HTT P42858 1/20 0.36
ATM Q13315 1/20 0.36
NR1I2 O75469 1/20 0.35
LMNA P02545 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
ADRA2A P08913 1/20 0.35
OPRK1 P41145 1/20 0.35
HTR2B P41595 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11801495 1.00 SPHK2 (0.39) SPHK2SPHK1CETPSCN5ASCN9A
SCHEMBL5616777 0.88 CETP (0.39) SPHK2SPHK1CETPMEN1MAPT
SCHEMBL676161 0.87 TBXAS1 (0.33) MEN1KMT2AHDAC6
SCHEMBL506229 0.87 TBXAS1 (0.33) MEN1KMT2AHDAC6
SCHEMBL675034 0.87 TBXAS1 (0.33) MEN1KMT2AHDAC6
SCHEMBL5616689 0.85 MEN1 (0.32) MEN1KMT2A
SCHEMBL39754 0.83 MTNR1A (0.31)
SCHEMBL2898593 0.78 SCN5A (0.41) SPHK2SPHK1CETPSCN5ASCN9A
SCHEMBL2762138 0.76 SPHK2 (0.40) SPHK2SPHK1SCN5ASCN9AMEN1
SCHEMBL5031163 0.73 CYP4F2 (0.41) SPHK1CETPMEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7504200-B2 Combined use of a lubricating silicon-containing acrylic polymer and a fluorosurfactant, such as diperfluorononyl polyethylene glycol, greatly improves wear and stain resistances KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2009-03-17 US disclosed
US-7427467-B2 Silver salt photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-09-23 US disclosed
US-20080187875-A1 PHOTOTHERMOGRAPHIC MATERIAL KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-08-07 US disclosed
EP-1953592-A1 Photothermographic material Konica Minolta Medical & Graphic, Inc. (JP) 2008-08-06 EP disclosed
EP-1717635-A1 Silver salt photothermographic dry imaging material Konica Minolta Medical & Graphic Inc. (JP) 2006-11-02 EP disclosed
US-20060240367-A1 Silver salt photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2006-10-26 US disclosed