Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3987561 | 0.90 | MAPK1 (0.36) | MAPK1OPRK1RENKMT2AMEN1 | |
| SCHEMBL13795951 | 0.90 | REN (0.34) | MAPK1OPRK1RENKMT2AMEN1 | |
| SCHEMBL4656232 | 0.85 | OPRK1 (0.42) | OPRK1 | |
| SCHEMBL13979534 | 0.85 | OPRK1 (0.42) | OPRK1 | |
| SCHEMBL3995150 | 0.82 | CYP3A4 (0.35) | MAPK1CYP3A4PIN1MC4RMC3R | |
| SCHEMBL3988530 | 0.81 | PTPRB (0.36) | REN | |
| SCHEMBL13796750 | 0.81 | PTPRB (0.36) | REN | |
| SCHEMBL3990129 | 0.81 | OPRK1 (0.35) | MAPK1CYP3A4OPRK1RENKMT2A | |
| SCHEMBL13796438 | 0.79 | MC4R (0.37) | MAPK1CYP3A4PIN1MC4RMC3R | |
| SCHEMBL3994927 | 0.79 | SYK (0.32) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553969-B1 | Substituted phenethylamine derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-06-30 | — | — | US | disclosed |
| EP-1149843-A1 | SUBSTITUTED PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-10-31 | — | — | EP | disclosed |