Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13979534 | 1.00 | OPRK1 (0.42) | OPRK1FNTAFNTBMMP2 | |
| SCHEMBL3989366 | 0.85 | MAPK1 (0.36) | OPRK1 | |
| SCHEMBL13795951 | 0.82 | REN (0.34) | OPRK1 | |
| SCHEMBL3987561 | 0.81 | MAPK1 (0.36) | OPRK1 | |
| SCHEMBL4657183 | 0.79 | CTSL (0.47) | — | |
| SCHEMBL4657191 | 0.79 | APP (0.40) | FNTAFNTB | |
| SCHEMBL3989149 | 0.75 | BACE1 (0.36) | OPRK1 | |
| SCHEMBL3988530 | 0.74 | PTPRB (0.36) | — | |
| SCHEMBL13796750 | 0.74 | PTPRB (0.36) | — | |
| SCHEMBL4656413 | 0.73 | SYK (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1006122-B1 | PHENETHYLAMINE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2008-12-03 | — | — | EP | disclosed |
| US-6255285-B1 | GASTROINTESTINAL DISORDERS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-07-03 | — | — | US | disclosed |
| EP-1006122-A1 | PHENETHYLAMINE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-06-07 | — | — | EP | disclosed |