Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27645322 | 0.86 | THRA (0.58) | THRATHRBESR2ESR1 | |
| SCHEMBL27516433 | 0.84 | THRB (0.49) | KMT2AMEN1MAPTTHRATHRB | |
| SCHEMBL3985532 | 0.81 | HSP90AB1 (0.43) | KMT2AMEN1MAPTCYP3A4HTR2B | |
| SCHEMBL11589520 | 0.80 | THRA (0.49) | MAPTTHRATHRBESR2ALOX5 | |
| SCHEMBL675857 | 0.76 | CYP3A4 (0.50) | KMT2AMEN1THRATHRBCYP3A4 | |
| SCHEMBL9185748 | 0.76 | KMT2A (0.43) | KMT2AMEN1MAPTCYP3A4HTR2B | |
| SCHEMBL15799777 | 0.76 | THRB (0.57) | KMT2AMEN1MAPTTHRATHRB | |
| SCHEMBL1683378 | 0.75 | KMT2A (0.47) | KMT2AMEN1MAPTCYP3A4ALOX15 | |
| SCHEMBL28293837 | 0.75 | NPC1 (0.48) | KMT2AMEN1MAPTHPGD | |
| SCHEMBL9192605 | 0.74 | KMT2A (0.47) | KMT2AMEN1MAPTHTR2BPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009060209-A1 | 6,6-FUSED BICYCLIC AROMATIC COMPOUNDS AND THEIR THERAPEUTI USE | ARGENTA DISCOVERY LIMITED (GB) | 2009-05-14 | — | — | WO | disclosed |