SCHEMBL3992009

SCHEMBL3992009

C=C(CCC(F)(F)F)C(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TET2 Q6N021 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2975722 0.81 ALDH1A1 (0.34) ALDH1A1MAPT
SCHEMBL21777040 0.81 ALDH1A1 (0.34) ALDH1A1MAPT
SCHEMBL27800565 0.81 ALDH1A1 (0.41) ALDH1A1TET2TSHR
SCHEMBL9546116 0.80 ALDH1A1 (0.46) ALDH1A1MAPTTSHR
SCHEMBL28039689 0.80 ALDH1A1 (0.33) ALDH1A1
SCHEMBL11603931 0.79 ALDH1A1 (0.52) ALDH1A1TET2TSHR
SCHEMBL263183 0.79
SCHEMBL28074471 0.79 ALDH1A1 (0.39) ALDH1A1TET2TSHR
SCHEMBL2468506 0.78 ALDH1A1 (0.42) ALDH1A1TET2MAPT
SCHEMBL9578500 0.78 HTT (0.42) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1486800-B1 NON-BIREFRINGENT OPTICAL RESIN MATERIAL AND ITS PRODUCING METHOD KOIKE YASUHIRO (JP) 2009-06-03 EP disclosed
US-7485676-B2 Non-birefringent optical resin material and its producing method KOIKE YASUHIRO 2009-02-03 US disclosed
US-20070166250-A1 COSMETIC POLYMER COMPOSITION AND COSMETIC MITSUBISHI CHEMICAL CORPORATION 2007-07-19 US disclosed
US-20050119389-A1 Non-birefringent optical resin material and its producing method KOIKE YASUHIRO (JP) 2005-06-02 US disclosed
EP-1486800-A1 NON-BIREFRINGENT OPTICAL RESIN MATERIAL AND ITS PRODUCING METHOD KOIKE, Yasuhiro (JP) 2004-12-15 EP disclosed
US-20040223933-A1 Cosmetic polymer composition and cosmetic MITSUBISHI CHEMICAL CORPORATION 2004-11-11 US disclosed
EP-1440680-A1 COSMETIC POLYMER COMPOSITION AND COSMETIC Mitsubishi Chemical Corporation (JP) 2004-07-28 EP disclosed
EP-0982590-B1 Labeled conjugate and detection method using the same NITTO DENKO CORP (JP) 2003-11-19 EP disclosed
EP-0982590-A1 Labeled conjugate and detection method using the same NITTO DENKO CORPORATION (JP) 2000-03-01 EP disclosed
WO-1993023773-A1 PROCESS FOR PREPARATION OF OXYGEN PERMEABLE POLYMER MATERIAL CIBA-GEIGY AG (CH) 1993-11-25 WO disclosed
US-5235013-A Copolymerizing an alkene of 6-10 carbons having one double bond and a side chain methyl group and an acrylic or fluoroacrylic ester CIBA-GEIGY CORPORATION 1993-08-10 US disclosed
EP-0478261-A2 Process for producing oxygen-permeable polymer CIBA-GEIGY AG (CH) 1992-04-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070166250-A1 COSMETIC POLYMER COMPOSITION AND COSMETIC ERCC1, PCNA, CUTA ALDH1A1 1048/4885TET2 759/4885MAPT 338/4885
US-20040223933-A1 Cosmetic polymer composition and cosmetic PCNA, ERCC1, CUTA ALDH1A1 1133/4885TET2 755/4885MAPT 314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.