Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12500625 | 0.81 | APLNR (0.32) | APLNRMEN1KMT2A | |
| SCHEMBL12500624 | 0.81 | APLNR (0.32) | APLNRMEN1KMT2A | |
| SCHEMBL16465581 | 0.81 | NNMT (0.33) | APLNRMEN1KMT2A | |
| SCHEMBL14967249 | 0.74 | MAPK1 (0.37) | KMT2A | |
| SCHEMBL16058474 | 0.70 | HTR2A (0.34) | — | |
| SCHEMBL4380612 | 0.69 | NPC1 (0.56) | MEN1KMT2A | |
| SCHEMBL2226189 | 0.68 | — | — | |
| SCHEMBL16601169 | 0.68 | LMNA (0.51) | MEN1KMT2A | |
| SCHEMBL28461359 | 0.68 | CYP2D6 (0.36) | KMT2A | |
| SCHEMBL28461356 | 0.68 | CYP2D6 (0.36) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061785-A2 | LINEAR PYRIDAZINE AND PYRROLE COMPOUNDS, PROCESSES FOR OBTAINING THEM AND USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2009-05-27 | — | — | EP | claimed |
| WO-2008012441-A2 | LINEAR PYRIDAZINE AND PYRROLE COMPOUNDS, PROCESSES FOR OBTAINING THEM AND USES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2008-01-31 | — | — | WO | claimed |