SCHEMBL3993933

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4605262	0.90	MAPT (0.51)	MAPTLMNAGAAALDH1A1MEN1
	SCHEMBL14217569	0.90	MAPT (0.61)	MAPTLMNAGAAALDH1A1MEN1
	SCHEMBL13337731	0.89	ALDH1A1 (0.61)	MAPTLMNAGAAALDH1A1MEN1
	SCHEMBL3920972	0.88	MEN1 (0.70)	MAPTLMNAGAAALDH1A1MEN1
	SCHEMBL3919729	0.88	ALDH1A1 (0.65)	MAPTLMNAGAAALDH1A1MEN1
	SCHEMBL4507527	0.87	MAPT (0.62)	MAPTLMNAGAAALDH1A1MEN1
	SCHEMBL3931598	0.87	MAPT (0.69)	MAPTLMNAGAAALDH1A1MEN1
	SCHEMBL3931603	0.86	MAPT (0.68)	MAPTLMNAGAAALDH1A1MEN1
	SCHEMBL3423881	0.86	MAPT (0.56)	MAPTLMNAGAAALDH1A1MEN1
	SCHEMBL3993937	0.84	GRM1 (0.62)	MEN1KMT2AMAPK10MAPK9GRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.