Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.46 |
| ▸ | STAT3 | P40763 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.46 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.46 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3993933 | 0.90 | MAPT (0.64) | MAPTGAALMNAMAPK10MAPK9 | |
| SCHEMBL3352115 | 0.89 | MEN1 (0.56) | MAPTGAALMNAMEN1KMT2A | |
| SCHEMBL3993937 | 0.82 | GRM1 (0.62) | MAPK10MAPK9MEN1KMT2AGRM1 | |
| SCHEMBL3353901 | 0.82 | MEN1 (0.47) | MAPTGAALMNAMAPK10MAPK9 | |
| SCHEMBL3353906 | 0.82 | MEN1 (0.47) | MAPTGAALMNAMAPK10MAPK9 | |
| SCHEMBL13337731 | 0.81 | ALDH1A1 (0.61) | MAPTGAALMNAMAPK10MAPK9 | |
| SCHEMBL14217569 | 0.80 | MAPT (0.61) | MAPTGAALMNAMAPK10MAPK9 | |
| SCHEMBL3920972 | 0.79 | MEN1 (0.70) | MAPTGAALMNAMAPK10MEN1 | |
| SCHEMBL3919729 | 0.78 | ALDH1A1 (0.65) | MAPTGAALMNAMEN1KMT2A | |
| SCHEMBL3423881 | 0.78 | MAPT (0.56) | MAPTGAALMNAMAPK10MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753512-B1 | TETRAHYDROPYRIDOTHIOPHENES | NYCOMED GMBH (DE) | 2008-07-09 | — | — | EP | claimed |