Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CDK2 | P24941 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | FYN | P06241 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15782762 | 0.73 | DEPTOR (0.31) | — | |
| SCHEMBL7802339 | 0.70 | ALDH1A1 (0.52) | LMNAALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL17715571 | 0.70 | HPGD (0.52) | LMNAALDH1A1HPGDALOX15HSD17B10 | |
| Pyrogallol SCHEMBL3532 | 0.66 | — | — | |
| Pyrogallol SCHEMBL170157 | 0.66 | ALDH1A1 (1.00) | LMNAALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL3567350 | 0.65 | ERN1 (0.48) | LMNAALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL3567348 | 0.65 | LMNA (0.46) | LMNAALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL16918790 | 0.65 | CXCR1 (0.39) | LMNAALDH1A1HPGDCA2EGFR | |
| Boric Acid SCHEMBL14940655 | 0.65 | HPGD (0.46) | LMNAALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL9055550 | 0.65 | ALDH1A1 (0.50) | LMNAALDH1A1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797087-A4 | CARBO- AND HETERO-CYCLIC ANTIBIOTICS AND USE THEREOF | ULYSSES PHARMACEUTICAL PRODUCT (CA) | 2009-06-03 | — | — | EP | disclosed |
| US-20080188499-A1 | Carbo- and Hetero-Cyclic Antibiotics and Use Thereof | ULYSSES PHARMACEUTICAL PRODUCTS INC. (CA) | 2008-08-07 | — | — | US | disclosed |
| EP-1797087-A1 | CARBO- AND HETERO-CYCLIC ANTIBIOTICS AND USE THEREOF | Ulysses Pharmaceuticals Products Inc. (CA) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006032138-A1 | CARBO- AND HETERO-CYCLIC ANTIBIOTICS AND USE THEREOF | ULYSSES PHARMACEUTICAL PRODUCTS INC. (CA) | 2006-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188499-A1 | Carbo- and Hetero-Cyclic Antibiotics and Use Thereof | SLC7A1, CYP2C19, ABCB11 | LMNA 3823/4885ALDH1A1 2455/4885HPGD 1037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.