Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26145075 | 0.86 | KDM4E (0.56) | KDM4EHIF1AMAPK1PAOXTSHR | |
| SCHEMBL2126880 | 0.79 | CA1 (0.43) | CA1CA2CA12CA9CA4 | |
| SCHEMBL10055320 | 0.78 | CA2 (0.41) | TSHRALDH1A1CA1CA2CA12 | |
| SCHEMBL8515872 | 0.78 | KDM4E (0.50) | KDM4EHIF1AMAPK1PAOXTSHR | |
| SCHEMBL468761 | 0.78 | KDM4E (0.56) | KDM4EHIF1AMAPK1PAOXTSHR | |
| SCHEMBL3657984 | 0.78 | CA1 (0.45) | CA1CA2CA12CA9CA4 | |
| SCHEMBL20942602 | 0.77 | MEN1 (0.54) | ALDH1A1CA1CA2CA12CA9 | |
| SCHEMBL2780184 | 0.76 | KDM4E (0.54) | KDM4EHIF1AMAPK1PAOXTSHR | |
| Calcium SCHEMBL2590651 | 0.76 | KDM4E (0.54) | KDM4EHIF1AMAPK1PAOXTSHR | |
| SCHEMBL18072246 | 0.76 | CA1 (0.40) | CA1CA2CA12CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291921-A1 | INTEGRASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2009-11-26 | — | — | US | claimed |
| WO-2009067541-A2 | INTEGRASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2009-05-28 | — | — | WO | claimed |
| US-11773058-B2 | Sulfonamide carboxamide compounds | INFLAZOME LIMITED (IE) | 2023-10-03 | — | — | US | disclosed |
| US-11773058-B2 | Sulfonamide carboxamide compounds | INFLAZOME LIMITED (IE) | 2023-10-03 | — | — | US | disclosed |
| US-11773058-B2 | Sulfonamide carboxamide compounds | INFLAZOME LIMITED (IE) | 2023-10-03 | — | — | US | disclosed |
| CN-110461951-B | Composition, dichroic material, light-absorbing anisotropic film, laminate, and image display device | 富士胶片株式会社 | 2022-04-08 | — | — | CN | disclosed |
| EP-3795568-A1 | FLUORINATED LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | Pharmakea, Inc. (US) | 2021-03-24 | — | — | EP | disclosed |
| EP-3265456-B1 | FLUORINATED LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA INC (US) | 2020-11-18 | — | — | EP | disclosed |
| US-20200331850-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-10-22 | — | — | US | disclosed |
| US-20200331850-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-10-22 | — | — | US | disclosed |
| CN-111107903-A | Novel sulfonamide carboxamide compounds | 英夫拉索姆有限公司 | 2020-05-05 | — | — | CN | disclosed |
| US-20090291921-A1 | INTEGRASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2009-11-26 | — | — | US | disclosed |
| WO-2009067541-A2 | INTEGRASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2009-05-28 | — | — | WO | disclosed |
| US-20080206672-A1 | Optical Information Recording Medium | FUJIFILM CORPORATION (JP) | 2008-08-28 | — | — | US | disclosed |
| US-20080165668-A1 | RECORDING MEDIUM AND INFORMATION RECORDING AND REPRODUCING METHOD USING THE SAME | FUJIFILM CORPORATION | 2008-07-10 | — | — | US | disclosed |
| EP-1886828-A1 | OPTICAL INFORMATION RECORDING MEDIUM | FUJIFILM Corporation (JP) | 2008-02-13 | — | — | EP | disclosed |
| US-20060194151-A1 | Recording medium and information recording and reproducing method using the same | FUJI PHOTO FILM CO., LTD. | 2006-08-31 | — | — | US | disclosed |
| US-7058001-B2 | Recording medium and information recording and reproducing method using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2006-06-06 | — | — | US | disclosed |
| US-20020118627-A1 | Recording medium and information recording and reproducing method using the same | FUJIFILM CORPORATION (JP) | 2002-08-29 | — | — | US | disclosed |
| EP-1130585-A2 | Recording medium and information recording and reproducing method using the same | Fuji Photo Film Co., Ltd. (JP) | 2001-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291921-A1 | INTEGRASE INHIBITORS | TYMP, DNTT, PAICS | KDM4E 1971/4885HIF1A 4233/4885MAPK1 3463/4885 |
| US-11773058-B2 | Sulfonamide carboxamide compounds | NLRP3, NOD1, NLRP1 | KDM4E 2420/4885HIF1A 1397/4885MAPK1 3287/4885 |
| US-20200331850-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | NLRP3, NOD1, NLRP1 | KDM4E 2501/4885HIF1A 1282/4885MAPK1 3059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.