Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2361806 | 0.85 | CYP1A2 (0.49) | ALDH1A1HSD17B10ALOX12TSHRL3MBTL1 | |
| SCHEMBL39946 | 0.84 | ESR1 (0.44) | ALDH1A1TSHRCYP1A2MAPTHTT | |
| Benzene SCHEMBL27985319 | 0.84 | ESR1 (0.44) | ALDH1A1TSHRCYP1A2MAPTHTT | |
| SCHEMBL9818045 | 0.84 | ESR1 (0.44) | ALDH1A1TSHRCYP1A2MAPTHTT | |
| SCHEMBL1880100 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HSD17B10ALOX12TSHRL3MBTL1 | |
| SCHEMBL6406224 | 0.82 | CA12 (0.45) | ALDH1A1TSHRL3MBTL1MAPK1CYP1A2 | |
| Ammonia Solution, Strong SCHEMBL28398668 | 0.82 | ESR1 (0.43) | ALDH1A1ALOX12TSHRCYP1A2MAPT | |
| Water SCHEMBL10786878 | 0.82 | ESR1 (0.43) | ALDH1A1TSHRCYP1A2MAPTHTT | |
| Methane SCHEMBL27634949 | 0.82 | ESR1 (0.43) | ALDH1A1TSHRCYP1A2MAPTHTT | |
| SCHEMBL3265246 | 0.80 | ALDH1A1 (0.41) | ALDH1A1ALOX12TSHRL3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156441-A1 | Cycloalkyl phenylenediamines as deposit control agents for lubricants | GREAT LAKES CHEMICAL GLOBAL, INC. | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156441-A1 | Cycloalkyl phenylenediamines as deposit control agents for lubricants | C5, C9, C1S | ALDH1A1 1125/4885HSD17B10 565/4885ALOX12 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.