Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3997685 | 0.78 | HDAC1 (0.50) | HDAC1HDAC2NR4A2HTR3AKDM4E | |
| SCHEMBL4131795 | 0.74 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL3996474 | 0.70 | NR4A2 (0.64) | HDAC1HDAC2NR4A2HTR3AHTR7 | |
| SCHEMBL4241227 | 0.68 | SIGMAR1 (0.45) | KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL27806604 | 0.68 | PARP1 (0.53) | HDAC1HDAC2NR4A2HTR7GAA | |
| SCHEMBL579555 | 0.66 | NR4A2 (0.65) | HDAC1HDAC2NR4A2HTR3AHTR7 | |
| SCHEMBL4003298 | 0.66 | CHEK2 (0.48) | HDAC1 | |
| SCHEMBL27381209 | 0.66 | LIPG (0.53) | HDAC1HDAC2NR4A2HTR3AHTR7 | |
| SCHEMBL10321788 | 0.66 | NR4A2 (0.64) | HDAC1HDAC2NR4A2HTR3AKDM4E | |
| SCHEMBL407789 | 0.66 | HDAC1 (0.65) | HDAC1HDAC2NR4A2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071577-A1 | OXADIAZOLE DERIVATIVES AND THEIR USE AS NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2009-06-11 | — | — | WO | disclosed |