SCHEMBL39999

SCHEMBL39999

NCCOCCOCCOCCOCCOCCOCCOCCO

nearest known ligand 0.69

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
TSHR P16473 3/20 0.62
MAPK1 P28482 1/20 0.62
THRB P10828 1/20 0.44
HTT P42858 1/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 2/20 0.43
APP P05067 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28443003 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL3182791 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL31395676 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL3177549 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL15500293 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL313703 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL16329524 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL16329522 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL21479469 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL2048089 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4563586-A1 NEW INHIBITORS OF LRRK2/PP1 INTERACTION Université Paris Cité (FR) 2025-06-04 EP claimed
CN-118326399-A Low-scratch and easy-to-clean tungsten plug chemical mechanical polishing solution and application thereof 万华化学集团电子材料有限公司 2024-07-12 CN claimed
EP-4728279-A2 USE OF CUSTOM-DESIGNED PEPTIDES FOR MASS CALIBRATION DH Technologies Development Pte. Ltd. (SG) 2026-04-22 EP disclosed
EP-4719381-A1 LIGAND-POLAR DRUG CONJUGATES Tripartite Therapeutics Inc. (TW) 2026-04-08 EP disclosed
EP-4563586-A1 NEW INHIBITORS OF LRRK2/PP1 INTERACTION Université Paris Cité (FR) 2025-06-04 EP disclosed
US-20250032635-A1 LIGAND-POLAR DRUG CONJUGATES TRIPARTITE THERAPEUTICS INC. (TW) 2025-01-30 US disclosed
WO-2024257055-A2 USE OF CUSTOM-DESIGNED PEPTIDES FOR MASS CALIBRATION DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) 2024-12-19 WO disclosed
US-12037641-B2 Modified nucleotide reagents PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2024-07-16 US disclosed
CN-118326399-A Low-scratch and easy-to-clean tungsten plug chemical mechanical polishing solution and application thereof 万华化学集团电子材料有限公司 2024-07-12 CN disclosed
US-20240025923-A1 BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF NURIX THERAPEUTICS INC (US) 2024-01-25 US disclosed
US-11827624-B2 Covalent immune recruiter compounds for immune cell recognition and associated uses MCMASTER UNIVERSITY (CA) 2023-11-28 US disclosed
US-20150164876-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. 2015-06-18 US disclosed
US-8916569-B2 Compounds and methods for inhibiting phosphate transport ARDELYX, INC. (US) 2014-12-23 US disclosed
US-20140023611-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. 2014-01-23 US disclosed
US-20130336920-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. (US) 2013-12-19 US disclosed
EP-2590656-A2 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT Ardelyx, Inc. (US) 2013-05-15 EP disclosed
EP-2591354-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT Ardelyx, Inc. (US) 2013-05-15 EP disclosed
US-20130052130-A1 Branched Discreet PEG Constructs UNIVERSITY OF WASHINGTON (US) 2013-02-28 US disclosed
WO-2012054110-A2 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. (US) 2012-04-26 WO disclosed
WO-2012006475-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT ARDELYX, INC. (US) 2012-01-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037641-B2 Modified nucleotide reagents POLL, POLN, POLM MEN1 4374/4885KMT2A 2859/4885TSHR 3276/4885
US-20150164876-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT SLC34A2, SLC34A1, SLC10A2 MEN1 2404/4885KMT2A 4695/4885TSHR 3105/4885
US-11827624-B2 Covalent immune recruiter compounds for immune cell recognition and associated uses CD74, CD4, HLA-A MEN1 4065/4885KMT2A 3495/4885TSHR 2277/4885
US-20140023611-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT SLC10A2, SLC34A2, SLC34A3 MEN1 3183/4885KMT2A 4830/4885TSHR 4326/4885
US-20130336920-A1 COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT SLC34A2, SLC34A1, SLC10A2 MEN1 2404/4885KMT2A 4695/4885TSHR 3105/4885
US-20240025923-A1 BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF TTK, HIPK1, HIPK2 MEN1 3081/4885KMT2A 778/4885TSHR 4150/4885
US-20250032635-A1 LIGAND-POLAR DRUG CONJUGATES CD274, SELPLG, PDCD1LG2 MEN1 2090/4885KMT2A 4242/4885TSHR 648/4885
US-20130052130-A1 Branched Discreet PEG Constructs BTD, DNPEP, IDUA MEN1 3511/4885KMT2A 2440/4885TSHR 1649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.