SCHEMBL2048089

SCHEMBL2048089

NCCOCCOCCOCCOCCOCCO

nearest known ligand 0.69

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
TSHR P16473 3/20 0.62
MAPK1 P28482 1/20 0.62
THRB P10828 1/20 0.44
HTT P42858 1/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 2/20 0.43
APP P05067 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28443003 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL3182791 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL31395676 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL3177549 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL15500293 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL313703 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL16329524 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL39999 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL16329522 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB
SCHEMBL21479469 1.00 MEN1 (0.69) MEN1KMT2ATSHRMAPK1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4563586-A1 NEW INHIBITORS OF LRRK2/PP1 INTERACTION Université Paris Cité (FR) 2025-06-04 EP claimed
US-20260110690-A1 PROBE AND METHODS FOR IDENTIFYING HOST CELL PROTEIN IMPURITIES REGENERON PHARMACEUTICALS, INC. 2026-04-23 US disclosed
US-20260085058-A1 DEGRADERS OF SON OF SEVENLESS HOMOLOG 1 YUAN YU (US) 2026-03-26 US disclosed
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF ANNEXON INC (US) 2026-03-12 US disclosed
US-20260055097-A9 NRF2 PROTEIN DEGRADERS GANYMEDE ONCOLOGY INC (US) 2026-02-26 US disclosed
US-12540945-B2 Probe and method for identifying host cell protein impurities REGENERON PHARMACEUTICALS, INC. (US) 2026-02-03 US disclosed
US-12509474-B2 Inhibitors of complement factors and uses thereof ANNEXON, INC. (US) 2025-12-30 US disclosed
US-20250362432-A1 OPHTHALMIC DEVICES CONTAINING PHOTOSTABLE MIMICS OF MACULAR PIGMENT AND OTHER VISIBLE LIGHT FILTERS JOHNSON & JOHNSON VISION CARE (US) 2025-11-27 US disclosed
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2025-10-23 US disclosed
EP-4613773-A2 IRAK DEGRADERS AND USES THEREOF Kymera Therapeutics, Inc. (US) 2025-09-10 EP disclosed
EP-2336315-A2 Enzymatic encoding methods for efficient synthesis of large libraries Nuevolution A/S (DK) 2011-06-22 EP disclosed
EP-1957644-B1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION AS (DK) 2010-12-01 EP disclosed
US-20090264300-A1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION A/S (DK) 2009-10-22 US disclosed
US-20090137773-A1 Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Forming Foams, and Foam Stabilizers ASEPSIS, INC. 2009-05-28 US disclosed
EP-1957644-A2 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES Nuevolution A/S (DK) 2008-08-20 EP disclosed
EP-1907343-A2 PRODUCTION PROCESSES AND SYSTEMS, COMPOSITIONS, SURFACTANTS, MONOMER UNITS, METAL COMPLEXES, PHOSPHATE ESTERS, GLYCOLS, AQUEOUS FILM FORMING FOAMS, AND FOAM STABILIZERS GREAT LAKES CHEMICAL CORPORATION (US) 2008-04-09 EP disclosed
WO-2007062664-A2 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION A/S (DK) 2007-06-07 WO disclosed
WO-2007016359-A2 PRODUCTION PROCESSES AND SYSTEMS, COMPOSITIONS, SURFACTANTS, MONOMER UNITS, METAL COMPLEXES, PHOSPHATE ESTERS, GLYCOLS, AQUEOUS FILM FORMING FOAMS, AND FOAM STABILIZERS GREAT LAKES CHEMICAL CORPORATION (US) 2007-02-08 WO disclosed
CN-1333746-A Molecular scaffold useful as a template comprising urethane linkages JOLLA PHARMA (US) 2002-01-30 CN disclosed
EP-0292128-A1 Improved DNA probes TAMIR BIOTECHNOLOGY LTD (IL) 1988-11-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250325673-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 MEN1 4055/4885KMT2A 445/4885TSHR 3319/4885
US-20090264300-A1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES RNGTT, DUT, EMG1 MEN1 3861/4885KMT2A 1082/4885TSHR 3837/4885
US-12509474-B2 Inhibitors of complement factors and uses thereof SSB, UACA, CFH MEN1 2996/4885KMT2A 4351/4885TSHR 437/4885
US-20260070932-A1 INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF CFH, CFB, C5 MEN1 2993/4885KMT2A 4631/4885TSHR 204/4885
US-20090137773-A1 Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Forming Foams, and Foam Stabilizers RFC3, RFC2, RFC4 MEN1 3736/4885KMT2A 2670/4885TSHR 2661/4885
US-20260110690-A1 PROBE AND METHODS FOR IDENTIFYING HOST CELL PROTEIN IMPURITIES BTD, LIPC, LPL MEN1 4868/4885KMT2A 3874/4885TSHR 1144/4885
US-20260055097-A9 NRF2 PROTEIN DEGRADERS KEAP1, NFE2L2, NFE2 MEN1 4667/4885KMT2A 2494/4885TSHR 2615/4885
US-12540945-B2 Probe and method for identifying host cell protein impurities BTD, LPL, LYPLA2 MEN1 4860/4885KMT2A 3985/4885TSHR 1331/4885
US-20260085058-A1 DEGRADERS OF SON OF SEVENLESS HOMOLOG 1 SOS1, KRAS, SOS2 MEN1 815/4885KMT2A 1078/4885TSHR 2924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.