Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14892312 | 0.97 | FAAH (0.52) | FAAHCA2DNM1CES1CES2 | |
| SCHEMBL28384730 | 0.97 | FAAH (0.52) | FAAHCA2DNM1CES1CES2 | |
| SCHEMBL17109068 | 0.97 | FAAH (0.52) | FAAHCA2DNM1CES1CES2 | |
| SCHEMBL19776015 | 0.97 | FAAH (0.52) | FAAHCA2DNM1CES1CES2 | |
| SCHEMBL470467 | 0.92 | LMNA (0.42) | FAAHCA2DNM1NPC1S1PR2 | |
| SCHEMBL4452469 | 0.80 | — | — | |
| SCHEMBL24575966 | 0.80 | FAAH (0.50) | FAAHCA2DNM1NPC1S1PR2 | |
| SCHEMBL9641486 | 0.80 | CA2 (0.45) | FAAHCA2 | |
| SCHEMBL14892276 | 0.80 | FAAH (0.44) | FAAHCA2DNM1CES1CES2 | |
| SCHEMBL17118120 | 0.80 | FAAH (0.44) | FAAHCA2DNM1CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110218167-B | N, N-dimethyl aryl sulfonamide derivative and application thereof in preventing and treating meloidogyne incognita | 河南科技大学 | 2021-09-24 | — | — | CN | claimed |
| CN-114195772-B | 1,2, 4-oxadiazole derivative containing 1,3, 4-thiadiazole unit, and preparation method and application thereof | 贵州大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-114195772-A | 1,2, 4-oxadiazole derivative containing 1,3, 4-thiadiazole unit and preparation method and application thereof | 贵州大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-110240533-B | Preparation method of N, N-dimethyl sulfonamide derivative | 河南科技大学 | 2022-03-18 | — | — | CN | disclosed |
| CN-110218167-B | N, N-dimethyl aryl sulfonamide derivative and application thereof in preventing and treating meloidogyne incognita | 河南科技大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-110218167-B | N, N-dimethyl aryl sulfonamide derivative and application thereof in preventing and treating meloidogyne incognita | 河南科技大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-110218167-B | N, N-dimethyl aryl sulfonamide derivative and application thereof in preventing and treating meloidogyne incognita | 河南科技大学 | 2021-09-24 | — | — | CN | disclosed |
| US-9187450-B2 | Substituted pyridine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-11-17 | — | — | US | disclosed |
| EP-2592076-B1 | SUBSTITUTED PYRIDINE COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2015-05-13 | — | — | EP | disclosed |
| US-20140213549-A9 | Substituted Pyridine Compound | UBE INDUSTRIES, LTD. (JP) | 2014-07-31 | — | — | US | disclosed |
| US-20140005143-A2 | Substituted PyridineCompound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-01-02 | — | — | US | disclosed |
| EP-2592076-A1 | SUBSTITUTED PYRIDINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-05-15 | — | — | EP | disclosed |
| US-20130109653-A1 | Substituted Pyridine Compound | UBE INDUSTRIES, LTD. (JP) | 2013-05-02 | — | — | US | disclosed |
| US-20120172367-A1 | MACROCYCLIC INTEGRASE INHIBITORS | ELANCO ANIMAL HEALTH IRELAND LIMITED (US) | 2012-07-05 | — | — | US | disclosed |
| EP-1696912-A4 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1696912-A2 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M Innovative Properties Company (US) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005079195-A2 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172367-A1 | MACROCYCLIC INTEGRASE INHIBITORS | CCNI, CCNY, CDK7 | FAAH 4719/4885CA2 4539/4885DNM1 2443/4885 |
| US-20140213549-A9 | Substituted Pyridine Compound | CETP, MTTP, PRCP | FAAH 67/4885CA2 607/4885DNM1 1913/4885 |
| US-20140005143-A2 | Substituted PyridineCompound | CETP, MTTP, CES1 | FAAH 64/4885CA2 787/4885DNM1 2187/4885 |
| US-20130109653-A1 | Substituted Pyridine Compound | CETP, MTTP, PRCP | FAAH 67/4885CA2 607/4885DNM1 1913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.