Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252491 | 0.84 | SLC6A2 (0.45) | MAPK1ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL22010909 | 0.75 | LTA4H (0.41) | MAPK1ALDH1A1TDP1TSHRMEN1 | |
| SCHEMBL4003143 | 0.73 | HDAC8 (0.35) | ALDH1A1HDAC8 | |
| SCHEMBL899494 | 0.73 | MAPK1 (1.00) | MAPK1ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL29367556 | 0.73 | MAPK1 (1.00) | MAPK1ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL2750138 | 0.72 | MAPK1 (0.53) | MAPK1ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL5566257 | 0.68 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL4003856 | 0.67 | KMT2A (0.40) | ALDH1A1TDP1L3MBTL1TSHRSMN1; SMN2 | |
| SCHEMBL14938506 | 0.66 | ALOX15 (0.75) | MAPK1ALDH1A1TDP1L3MBTL1TSHR | |
| SCHEMBL7526745 | 0.66 | MAPK1 (0.74) | MAPK1ALDH1A1TDP1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066643-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008062012-A1 | PYRIDAZIN-4-YLMETHYL-SULFONAMIDES USED AS FUNGICIDES AND AGAINST ARTHROPODS | BASF SE (DE) | 2008-05-29 | — | — | WO | disclosed |