Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789164 | 1.00 | GABRA5 (0.51) | GABRA5GABRB2HSD17B10MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL8913011 | 0.99 | GABRA5 (0.50) | GABRA5GABRB2HSD17B10MAPTRAB9A | |
| SCHEMBL4824847 | 0.88 | GABRA5 (0.47) | GABRA5GABRB2HSD17B10MAPTRAB9A | |
| SCHEMBL8526934 | 0.86 | GABRA5 (0.49) | GABRA5GABRB2HSD17B10MAPTRAB9A | |
| SCHEMBL8896790 | 0.82 | NPC1 (0.47) | GABRA5GABRB2HSD17B10MAPTRAB9A | |
| SCHEMBL8896803 | 0.82 | NPC1 (0.47) | GABRA5GABRB2HSD17B10MAPTRAB9A | |
| Water SCHEMBL7801342 | 0.79 | GABRA5 (0.55) | GABRA5GABRB2HSD17B10MAPTRAB9A | |
| SCHEMBL5318279 | 0.78 | NPC1 (0.39) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5318277 | 0.78 | NPC1 (0.39) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9089346 | 0.78 | MAPT (0.44) | GABRA5GABRB2HSD17B10MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004753-A1 | ALKYLPHENOL DERIVATIVES HAVING PHYTOPATHOGENIC FUNGI ACTIVITIES | DONGBU HITEK CO., LTD. (KR) | 2007-01-11 | — | — | WO | claimed |
| EP-0533047-B1 | Preparation of a cephalosporin antibiotic using the synisomer of a thiazolyl intermediate | BRISTOL MYERS SQUIBB CO (US) | 2003-05-07 | — | — | EP | claimed |
| EP-0620228-B1 | Novel reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY LTD (KR) | 1998-03-11 | — | — | EP | claimed |
| US-7511135-B2 | Method for manufacture of ceftiofur | LUPIN LIMITED (IN) | 2009-03-31 | — | — | US | disclosed |
| US-20080207912-A1 | Method for manufacture of ceftiofur | LUPIN LIMITED | 2008-08-28 | — | — | US | disclosed |
| EP-1556388-B1 | A METHOD FOR MANUFACTURE OF CEFTIOFUR | LUPIN LTD (IN) | 2007-09-19 | — | — | EP | disclosed |
| CN-1321989-C | AE-active ester chemical synthesizing method | UNIV ZHEJIANG POLYTECHNIC (CN) | 2007-06-20 | — | — | CN | disclosed |
| WO-2007004753-A1 | ALKYLPHENOL DERIVATIVES HAVING PHYTOPATHOGENIC FUNGI ACTIVITIES | DONGBU HITEK CO., LTD. (KR) | 2007-01-11 | — | — | WO | disclosed |
| CN-1269776-C | Process for producing carboxylic acid derivative and condensing agent comprising quaternary ammonium salt | TOKUYAMA CORP (JP) | 2006-08-16 | — | — | CN | disclosed |
| US-20060149054-A1 | Method for manufacture of ceftiofur | LUPIN LIMITED (IN) | 2006-07-06 | — | — | US | disclosed |
| US-20050245498-A1 | Sterically-awkward beta-lactamase inhibitors | NORTHWESTERN UNIVERSITY | 2005-11-03 | — | — | US | disclosed |
| US-5502200-A | Reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY, LTD. (KR) | 1996-03-26 | — | — | US | disclosed |
| EP-0628561-A1 | Process for preparing cephalosporin compounds from reactive organic acid derivatives | LUCKY LTD. (KR) | 1994-12-14 | — | — | EP | disclosed |
| EP-0620228-A1 | Novel reactive thiophosphate derivatives of thia(dia)zole acetic acid and process for preparing the same | LUCKY LTD. (KR) | 1994-10-19 | — | — | EP | disclosed |
| US-4754031-A | Preparation of cephalosporins | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-28 | — | — | US | disclosed |
| EP-0062876-B1 | 2-OXO-1-(((SUBSTITUTED SULFONYL)AMINO)CARBONYL)AZETIDINES | E.R. Squibb & Sons, Inc. (US) | 1986-09-24 | — | — | EP | disclosed |
| US-4587047-A | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1986-05-06 | — | — | US | disclosed |
| EP-0108994-A1 | Process for preparation of optically active (4R)-substituted monocyclic beta-lactam compounds | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-05-23 | — | — | EP | disclosed |
| US-4426528-A | Purification of syn-(2-aminothiazol-4-yl)methoxyimino)acetic acid | ELI LILLY AND COMPANY (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0062876-A1 | 2-Oxo-1-(((substituted sulfonyl)amino)carbonyl)azetidines | E.R. Squibb & Sons, Inc. (US) | 1982-10-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207912-A1 | Method for manufacture of ceftiofur | APEH, COASY, PCMT1 | GABRA5 2826/4885GABRB2 2613/4885HSD17B10 485/4885 |
| US-20060149054-A1 | Method for manufacture of ceftiofur | APEH, COASY, PCMT1 | GABRA5 2706/4885GABRB2 2505/4885HSD17B10 499/4885 |
| US-20050245498-A1 | Sterically-awkward beta-lactamase inhibitors | AGL, MGAM, PGLS | GABRA5 1624/4885GABRB2 984/4885HSD17B10 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.