Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896803 | 1.00 | NPC1 (0.47) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL9600369 | 0.88 | SMN1; SMN2 (0.45) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL4824847 | 0.82 | GABRA5 (0.47) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL3999942 | 0.82 | GABRA5 (0.51) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL2789164 | 0.82 | GABRA5 (0.51) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL8768619 | 0.82 | GABRA5 (0.38) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL8913011 | 0.81 | GABRA5 (0.50) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL8378561 | 0.79 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL8378557 | 0.79 | ALDH1A1 (0.49) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL8723035 | 0.72 | MAPT (0.44) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0497978-B1 | CEPHALOSPORIN COMPOUNDS AND PRODUCTION THEREOF | KYOTO PHARMA IND (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5389625-A | Sweet taste; oral administering | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0497978-A1 | CEPHALOSPORIN COMPOUNDS AND PRODUCTION THEREOF | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1992-08-12 | — | — | EP | disclosed |