Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30578010 | 1.00 | F10 (0.69) | F10 | |
| SCHEMBL30578012 | 1.00 | F10 (0.69) | F10 | |
| SCHEMBL24418899 | 0.93 | F10 (0.64) | F10 | |
| SCHEMBL4003085 | 0.91 | F10 (0.78) | F10 | |
| SCHEMBL24418898 | 0.90 | F10 (0.70) | F10 | |
| SCHEMBL4003630 | 0.86 | F10 (0.64) | F10 | |
| SCHEMBL4009887 | 0.86 | F10 (0.65) | F10 | |
| SCHEMBL4002316 | 0.86 | F10 (0.65) | F10 | |
| SCHEMBL14146886 | 0.85 | F10 (0.65) | F10 | |
| SCHEMBL30578011 | 0.84 | F10 (0.63) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563786-B2 | Substituted thiophenecarboxamides, their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-07-21 | — | — | US | claimed |
| US-20060069082-A1 | Novel substituted thiophenecarboxamides, their preparation and their use as medicaments | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-03-30 | — | — | US | claimed |
| CN-116406266-A | 2- [ (thiophen-2-yl) carboxamido ] -N- (phenyl) -2-methylpropanamide derivatives and their use as pharmaceuticals | 勃林格殷格翰国际有限公司 | 2023-07-07 | — | — | CN | disclosed |
| US-11691960-B2 | 2-[thiophen-2-yl)formamido]-N-(phenyl)-2-methylpropanamide derivatives and the use thereof as medicament | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-07-04 | — | — | US | disclosed |
| US-11691960-B2 | 2-[thiophen-2-yl)formamido]-N-(phenyl)-2-methylpropanamide derivatives and the use thereof as medicament | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2023-07-04 | — | — | US | disclosed |
| US-20220144796-A1 | 2-[Thiophen-2-yl)formamido]-N-(phenyl)-2-methylpropanamide derivatives and the use therof as medicament | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-05-12 | — | — | US | disclosed |
| US-20220144796-A1 | 2-[Thiophen-2-yl)formamido]-N-(phenyl)-2-methylpropanamide derivatives and the use therof as medicament | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691960-B2 | 2-[thiophen-2-yl)formamido]-N-(phenyl)-2-methylpropanamide derivatives and the use thereof as medicament | IDO1, IDO2, INMT | F10 4273/4885 |
| US-20060069082-A1 | Novel substituted thiophenecarboxamides, their preparation and their use as medicaments | P2RY11, P2RX5, TPMT | F10 2756/4885 |
| US-20220144796-A1 | 2-[Thiophen-2-yl)formamido]-N-(phenyl)-2-methylpropanamide derivatives and the use therof as medicament | IDO1, IDO2, TPH1 | F10 3905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.