Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457600 | 0.89 | — | — | |
| SCHEMBL9065049 | 0.84 | HSD17B10 (0.45) | USP2 | |
| SCHEMBL460836 | 0.81 | USP2 (0.32) | USP2 | |
| SCHEMBL20437561 | 0.81 | SPHK1 (0.36) | — | |
| SCHEMBL25768131 | 0.81 | HSD17B10 (0.42) | — | |
| SCHEMBL373575 | 0.81 | USP2 (0.51) | USP2 | |
| SCHEMBL9419713 | 0.81 | USP2 (0.33) | USP2 | |
| SCHEMBL27273321 | 0.80 | USP2 (0.42) | USP2 | |
| SCHEMBL21483327 | 0.79 | USP2 (0.32) | USP2 | |
| SCHEMBL27273175 | 0.79 | USP2 (0.50) | USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8373000-B2 | Reacting a substituted epoxide with a lithium salt and acrylic acid to form a substituted hydroxy acrylate; chemical intermediates; ophthalmic devices, soft contact lenses | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-02-12 | — | — | US | disclosed |
| EP-1644386-B1 | PROCESS FOR THE PRODUCTION OF BIS(TRIMETHYLSILOXY)SILYLALKYLGLYCEROL METHACRYLATES | JOHNSON & JOHNSON VISION CARE (US) | 2009-06-03 | — | — | EP | disclosed |
| US-20080139829-A1 | Process for the production of bis(trimethylsilyloxy)silylalkylglycerol methacrylates | JOHNSON & JOHNSON VISION CARE, INC. | 2008-06-12 | — | — | US | disclosed |
| US-20070265460-A1 | PROCESS FOR THE PRODUCTION OF (TRIMETHYLSILYLOXY)SILYLALKYLGLYCEROL METHACRYLATES | JOHNSON & JOHNSON VISION CARE INC. | 2007-11-15 | — | — | US | disclosed |
| EP-1791848-A1 | PROCESS FOR THE PRODUCTION OF (TRIMETHYLSILYLOXY)SILYLALKYLGLYCEROL METHACRYLATES | Johnson and Johnson Vision Care, Inc. (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1644386-A1 | PROCESS FOR THE PRODUCTION OF BIS(TRIMETHYLSILOXY)SILYLALKYLGLYCEROL METHACRYLATES | Johnson & Johnson Vision Care, Inc. (US) | 2006-04-12 | — | — | EP | disclosed |
| WO-2006026245-A1 | PROCESS FOR THE PRODUCTION OF (TRIMETHYLSILYLOXY)SILYLALKYLGLYCEROL METHACRYLATES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2006-03-09 | — | — | WO | disclosed |
| US-20060047134-A1 | Process for the production of (trimethylsilyloxy)silylalkylglycerol methacrylates | JOHNSON & JOHNSON VISION CARE INC. | 2006-03-02 | — | — | US | disclosed |
| WO-2005005445-A1 | PROCESS FOR THE PRODUCTION OF BIS(TRIMETHYLSILOXY)SILYLALKYLGLYCEROL METHACRYLATES | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2005-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139829-A1 | Process for the production of bis(trimethylsilyloxy)silylalkylglycerol methacrylates | RIOK1, MGLL, RIOK2 | USP2 2943/4885 |
| US-20070265460-A1 | PROCESS FOR THE PRODUCTION OF (TRIMETHYLSILYLOXY)SILYLALKYLGLYCEROL METHACRYLATES | SGMS2, SGMS1, SMS | USP2 2402/4885 |
| US-20060047134-A1 | Process for the production of (trimethylsilyloxy)silylalkylglycerol methacrylates | SGMS2, SGMS1, SMS | USP2 2402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.