Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | IDE | P14735 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14690094 | 0.92 | NPC1 (0.48) | CHRM1MAPTNPC1HTTRAB9A | |
| SCHEMBL9450739 | 0.92 | NPC1 (0.48) | CHRM1MAPTNPC1HTTRAB9A | |
| SCHEMBL14690050 | 0.90 | MAPT (0.51) | CHRM1MAPTNPC1HTTRAB9A | |
| SCHEMBL8578111 | 0.89 | MAPT (0.45) | CHRM1MAPTNPC1HTTRAB9A | |
| SCHEMBL4293437 | 0.85 | MAPT (0.52) | CHRM1MAPTNPC1HTTRAB9A | |
| SCHEMBL28287460 | 0.84 | MAPT (0.66) | CHRM1MAPTNPC1HTTRAB9A | |
| SCHEMBL27973104 | 0.84 | MAPT (0.66) | CHRM1MAPTNPC1HTTRAB9A | |
| SCHEMBL13609827 | 0.83 | MAPT (0.45) | CHRM1MAPTNPC1HTTRAB9A | |
| SCHEMBL4651722 | 0.82 | KMT2A (0.46) | CHRM1MAPTNPC1HTTALDH1A1 | |
| SCHEMBL219154 | 0.82 | KMT2A (0.46) | CHRM1MAPTNPC1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773485-A4 | STABLE COMPOSITE MATERIAL COMPRISING SUPPORTED POROUS GELS | NATRIX SEPARATIONS INC (CA) | 2009-06-03 | — | — | EP | disclosed |
| EP-1758671-A4 | MEMBRANE STACKS | UNIV MCMASTER (CA) | 2007-06-06 | — | — | EP | disclosed |
| EP-1773485-A1 | STABLE COMPOSITE MATERIAL COMPRISING SUPPORTED POROUS GELS | McMaster University (CA) | 2007-04-18 | — | — | EP | disclosed |
| EP-1758671-A1 | MEMBRANE STACKS | McMaster University (CA) | 2007-03-07 | — | — | EP | disclosed |
| EP-1617936-A1 | COMPOSITE MATERIALS COMPRISING SUPPORTED POROUS GELS | McMASTER UNIVERSITY (CA) | 2006-01-25 | — | — | EP | disclosed |
| WO-2005120701-A1 | STABLE COMPOSITE MATERIAL COMPRISING SUPPORTED POROUS GELS | MCMASTER UNIVERSITY (CA) | 2005-12-22 | — | — | WO | disclosed |
| WO-2005097304-A1 | MEMBRANE STACKS | MCMASTER UNIVERSITY (CA) | 2005-10-20 | — | — | WO | disclosed |
| WO-2004073843-A1 | COMPOSITE MATERIALS COMPRISING SUPPORTED POROUS GELS | MCMASTER UNIVERSITY (CA) | 2004-09-02 | — | — | WO | disclosed |
| CN-1332188-A | Polymer gel for orally taken and colon released medicine and its prepn | UNIV CENTRAL CN SCI & TECH (CN) | 2002-01-23 | — | — | CN | disclosed |
| WO-1998001421-A1 | pH SENSITIVE HYDROGELS WITH ADJUSTABLE SWELLING KINETICS FOR COLON-SPECIFIC DELIVERY OF PEPTIDES AND PROTEINS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1998-01-15 | — | — | WO | disclosed |