Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | IDE | P14735 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4301816 | 0.88 | MAPT (0.50) | MAPTMEN1KMT2ANPC1HTT | |
| SCHEMBL4292105 | 0.88 | THRB (0.43) | MAPTMEN1KMT2ANPC1HTT | |
| SCHEMBL4000024 | 0.85 | CHRM1 (0.50) | MAPTMEN1KMT2ANPC1HTT | |
| SCHEMBL6725926 | 0.82 | MAPT (0.47) | MAPTMEN1KMT2ANPC1HTT | |
| SCHEMBL8578111 | 0.80 | MAPT (0.45) | MAPTMEN1KMT2ANPC1HTT | |
| SCHEMBL13609827 | 0.80 | MAPT (0.45) | MAPTMEN1KMT2ANPC1HTT | |
| SCHEMBL16752838 | 0.77 | MEN1 (0.55) | MAPTMEN1KMT2ANPC1HTT | |
| SCHEMBL9450739 | 0.77 | NPC1 (0.48) | MAPTNPC1HTTALDH1A1KDM4E | |
| SCHEMBL14690094 | 0.77 | NPC1 (0.48) | MAPTNPC1HTTALDH1A1KDM4E | |
| SCHEMBL14690050 | 0.76 | MAPT (0.51) | MAPTMEN1KMT2ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163650-A1 | POLYMER MATERIAL | MENICON CO., LTD. (JP) | 2021-06-03 | — | — | US | disclosed |
| EP-3822296-A1 | POLYMER MATERIAL | Menicon Co., Ltd. (JP) | 2021-05-19 | — | — | EP | disclosed |
| US-20130202551-A1 | IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS | MENICON CO., LTD. (JP) | 2013-08-08 | — | — | US | disclosed |
| EP-2581394-A1 | IONIC COMPOUND, COMPOSITION, CURED PRODUCT, HYDROGEL, AND OCULAR LENS | Menicon Co., Ltd. (JP) | 2013-04-17 | — | — | EP | disclosed |
| EP-1696257-B1 | CONTACT LENS MATERIAL | MENICON CO LTD (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-20090247662-A1 | Contact Lens Material | MATSUMOTO MASAHIRO | 2009-10-01 | — | — | US | disclosed |
| EP-1033590-B1 | Ocular lens material | MENICON CO LTD (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20070149699-A1 | Contact lens material | MENICON CO., LTD. (JP) | 2007-06-28 | — | — | US | disclosed |
| EP-1696257-A1 | CONTACT LENS MATERIAL | MENICON CO., LTD. (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-6329445-B1 | Ocular lens material | MENICON CO., LTD (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1033590-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 2000-09-06 | — | — | EP | disclosed |
| EP-0947856-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1999-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130202551-A1 | IONIC COMPOUND, COMPOSITION, CURED MATERIAL, HYDROGEL AND OPHTHALMIC LENS | CRYZ, CRYAA, VIL1 | MAPT 3975/4885MEN1 1583/4885KMT2A 3332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.