Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429327 | 0.92 | LMNA (0.43) | TRPV1TRPA1LMNAPLA2G1BPLA2G2A | |
| SCHEMBL4006368 | 0.90 | TRPV1 (0.42) | TRPV1TRPA1LMNAPLA2G1BPLA2G2A | |
| SCHEMBL7093122 | 0.87 | CA12 (0.44) | TRPV1TRPA1LMNAALDH1A1S1PR2 | |
| SCHEMBL118217 | 0.84 | DNM1 (0.50) | TRPV1TRPA1LMNAALDH1A1 | |
| SCHEMBL19946200 | 0.84 | DNM1 (0.50) | TRPV1TRPA1LMNAALDH1A1 | |
| SCHEMBL19468478 | 0.84 | DNM1 (0.50) | TRPV1TRPA1LMNAALDH1A1 | |
| SCHEMBL1507436 | 0.84 | DNM1 (0.50) | TRPV1TRPA1LMNAALDH1A1 | |
| SCHEMBL3792319 | 0.84 | DNM1 (0.50) | LMNAALDH1A1GSR | |
| SCHEMBL19468521 | 0.84 | DNM1 (0.50) | TRPV1TRPA1LMNAALDH1A1 | |
| SCHEMBL19468447 | 0.84 | DNM1 (0.50) | TRPV1TRPA1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2109657-A1 | LUBRICATING OIL COMPOSITION | Showa Shell Sekiyu K. K. (JP) | 2009-10-21 | — | — | EP | disclosed |
| WO-2009074667-A1 | LUBRICATING OIL COMPOSITION | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2009-06-18 | — | — | WO | disclosed |
| WO-2008095966-A1 | LUBRICATING OIL COMPOSITION | SHOWA SHELL SEKIYU K.K. (JP) | 2008-08-14 | — | — | WO | disclosed |