Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000198 | 0.92 | TRPV1 (0.42) | LMNATRPV1TRPA1ALDH1A1PLA2G1B | |
| SCHEMBL24957 | 0.86 | — | — | |
| SCHEMBL15208926 | 0.86 | NFKB1 (0.40) | LMNABLMGSRNFKB1HTR2A | |
| SCHEMBL28492245 | 0.84 | LMNA (0.46) | LMNABLM | |
| SCHEMBL6277716 | 0.83 | LMNA (0.48) | LMNATRPV1TRPA1BLMALDH1A1 | |
| Hydrochloric Acid SCHEMBL2862130 | 0.83 | — | — | |
| Bromide SCHEMBL1789440 | 0.83 | — | — | |
| SCHEMBL238918 | 0.83 | NFKB1 (0.43) | LMNABLMGSRNFKB1HTR2A | |
| SCHEMBL4006368 | 0.82 | TRPV1 (0.42) | LMNATRPV1TRPA1ALDH1A1PLA2G1B | |
| SCHEMBL18085360 | 0.81 | LMNA (0.46) | LMNABLMALDH1A1PLA2G1BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368719-A2 | Novel analogs of peptidase substrates | MERRELL PHARMACEUTICALS INC. (US) | 1990-05-16 | — | — | EP | disclosed |