Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18755105 | 0.83 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1L3MBTL1HIF1ANPSR1 | |
| SCHEMBL16014770 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1NPSR1KMOHSD11B1 | |
| SCHEMBL13226021 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1KCNN4BRD4HIF1A | |
| SCHEMBL1531326 | 0.81 | PDE10A (0.47) | SMN1; SMN2ALDH1A1L3MBTL1HIF1ANPSR1 | |
| SCHEMBL1630077 | 0.81 | HIF1A (0.48) | SMN1; SMN2ALDH1A1KCNN4L3MBTL1HIF1A | |
| SCHEMBL12763610 | 0.78 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1KCNN4L3MBTL1 | |
| SCHEMBL12724941 | 0.78 | ALOX5AP (0.43) | SMN1; SMN2ALDH1A1KCNN4L3MBTL1HIF1A | |
| SCHEMBL926841 | 0.77 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1HIF1ANPSR1RXFP1 | |
| SCHEMBL4005594 | 0.75 | LMNA (0.47) | SMN1; SMN2ALDH1A1L3MBTL1HIF1AHTT | |
| SCHEMBL2666044 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KCNN4L3MBTL1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009077485-A2 | 1(2)H-TETRAZOL-5-YL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INTERNACIONAL, S.A. (ES) | 2009-06-25 | — | — | WO | disclosed |
| WO-2009077485-A2 | 1(2)H-TETRAZOL-5-YL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | FERRER INTERNACIONAL, S.A. (ES) | 2009-06-25 | — | — | WO | disclosed |
| EP-2072514-A1 | 1(2)H-tetrazol-5-yl-phenyl-oxazolidinones as antibacterial agents | Ferrer Internacional, S.A. (ES) | 2009-06-24 | — | — | EP | disclosed |
| EP-2072514-A1 | 1(2)H-tetrazol-5-yl-phenyl-oxazolidinones as antibacterial agents | Ferrer Internacional, S.A. (ES) | 2009-06-24 | — | — | EP | disclosed |